Results 121 to 130 of about 330,789 (295)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Cytocentrifugation conditions affecting the differential cell count in bronchoalveolar lavage fluid

, 2000
OBJECTIVE: To investigate variations in speed, duration and acceleration rate of the Cytospin 3 cytocentrifuge (Shannon, scientific Ltd., Astmoor, England) on the differential cell count of bronchoalveolar lavage (BAL)fluid samples.STUDY DESIGN: BAL ...
Bruggeman, C.A.M.V.A., De Brauwer, E.I.G.B., Jacobs, J.A., Drent, M., Nieman, F.H.M., Wagenaar, S.S.   +5 more
core  

Machine Learning Approach for Early Lactation Mastitis Diagnosis Using Total and Differential Somatic Cell Counts

Animals
Dairy herds around the world are undergoing several changes. Herd sizes are increasing, as are both milk yield and quality. The implementation of new technologies in various domains of dairy production is leading to an increase in the quantity of data ...
Alfonso Zecconi, Francesca Zaghen, Gabriele Meroni, Flavio Sommariva, Silvio Ferrari, Valerio Sora   +5 more
doaj   +1 more source

Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India. [PDF]

Interdiscip Toxicol, 2018
Mukherjee S, Ray M, Ray S.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A computer-aided system for differential count from peripheral blood cell images

, 2016
The differential count and analysis of blood cells in microscope images can provide useful information concerning the health of patients. There are three major blood cell types, namely, erythrocytes (RBCs), leukocytes (WBCs), and platelets.
Cecilia Di Ruberto, DI RUBERTO, CECILIA, FENU, GIANNI, Lorenzo Putzu, PUTZU, LORENZO, Gianni Fenu, Andrea Loddo, LODDO, ANDREA   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Clinical utility of hematological parameters in aplastic anemia

Scientific Reports
Hematological parameters available on automated hematology analyzers have been shown to be useful indicators for hematological disorders. However, extensive studies especially in aplastic anemia for these indices are sparse.
Lizhong Zhang, Xiaonan Han, Qiujuan Zhu, Yu Qin, Yanan Jia   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Neutrophil count is the most important prognostic component of the differential white cell count in patients undergoing elective surgery for colorectal cancer

, 2015
Background: Systemic inflammatory scoring systems such as the NLR have been reported to have prognostic value in many solid organ cancers. The aim of this study was to examine the relationships between the components of the white cell count (WCC) and ...
McMillan, Donald C., Watt, David G., Martin, John C., Park, James H., Horgan, Paul G.   +4 more
core   +1 more source