Results 101 to 110 of about 6,359,259 (380)
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source
MedEdPORTAL, 2013 This 90-minute session seeks to provide a systematic framework for medical students relatively new to the differential diagnosis process. Via a combined lecture/case-based approach, the session presents basic clinical reasoning concepts and specific ...
Zev Waldman, Mary Ottolini
doaj +1 more source
Differential Diagnosis of Glaucoma
, 2019 Glaucoma is the most commonly acquired visual neuropathy and the main cause of irreversible loss of vision.It is characterized by degeneration of retinal ganglion cells resulting in morphology changes of the optic nerve head (ONH). It may be asymptomatic even at an advanced stage, so the diagnosis is often delayed.
Tzamouranis, Dorotheos Dimitrios +1 more
openaire +1 more source
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
Retroperitoneal tumor: pathological diagnosis and differential diagnosis [PDF]
Waike lilun yu shijian, 2022 WANG Jian
doaj +1 more source
Studia Medyczne, 2014 Sarcoidosis is a multi-organ granulomatous disease of unknown aetiology. Although it usually affects lungs and hilar lymph nodes, lesions can also affect other organs, including the organs of the nervous system.
Waldemar Brola +3 more
doaj +1 more source
Medical Dialogue Generation via Intuitive-then-Analytical Differential Diagnosis [PDF]
arXivMedical dialogue systems have attracted growing research attention as they have the potential to provide rapid diagnoses, treatment plans, and health consultations. In medical dialogues, a proper diagnosis is crucial as it establishes the foundation for future consultations. Clinicians typically employ both intuitive and analytic reasoning to formulate
arxiv