Differentially private distributed estimation and learning
IISE TransactionsWe study distributed estimation and learning problems in a networked environment where agents exchange information to estimate unknown statistical properties of random variables from their privately observed samples. The agents can collectively estimate the unknown quantities by exchanging information about their private observations, but they also ...
Marios Papachristou, M. Amin Rahimian
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Field Synergy Analysis and Fluid Flow Optimization of Tundish for Six Strands
Teshugang, 2009 The relation between distribution of temperature and fluid flow field in tundish for concasting has been analyzed by using theory of field synergy and the distribution of temperature and fluid flow field in a tundish for six strands at a steel works was ...
张美杰 +4 more
doaj
Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain. [PDF]
iScience, 2023 Suk TR +11 more
europepmc +1 more source
Differentially Private Distributed Inference
How can agents exchange information to learn from each other despite their privacy needs and security concerns? Consider healthcare centers that want to collaborate on a multicenter clinical trial, but are concerned about sharing sensitive patient information.
Marios Papachristou, M. Amin Rahimian
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Differential Distribution of Brain Metastases from Non-Small Cell Lung Cancer Based on Mutation Status. [PDF]
Brain Sci, 2023 Chen BT +8 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Glycan-related genes in human gut microbiota exhibit differential distribution and diversity in carbohydrate degradation and glycan synthesis. [PDF]
Front Mol Biosci, 2023 Takihara H, Okuda S.
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source