Results 101 to 110 of about 1,497,332 (283)
Differential equations satisfied by modular forms and K3 surfaces
We study differential equations satisfied by modular forms associated to $\Gamma_1\times\Gamma_2$, where $\Gamma_i (i=1,2)$ are genus zero subgroups of $SL_2(\mathbf R)$ commensurable with $SL_2(\mathbf Z)$, e.g., $\Gamma_0(N)$ or $\Gamma_0(N)^*$.
Yang, Yifan, Yui, Noriko
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
ON INITIAL BOUNDARY VALUE PROBLEMS FOR THE DEGENERATE 1D WAVE EQUATION
Initial boundary value problems in space-time rectangle for the following linear inhomogeneous degenerate wave equation of the second order smooth coefficient function a(x) vanishes in single points of segment.
Vladimir V. Borsch
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Functional differential equations close to differential equations [PDF]
when the lag function r(t) is nearly constant for large /, and has also asked for conditions on the function r under which all solutions approach zero as t—» oo. The purpose of this announcement is to initiate a study of various stability and oscillation problems for equations with perturbed lag functions, and to suggest that a modification of the ...
openaire +2 more sources
Arithmetic partial differential equations, I
Updated version of paper includes new results on ...
Buium, Alexandru, Simanca, Santiago R.
openaire +4 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source

