Results 101 to 110 of about 1,497,332 (283)

Differential equations satisfied by modular forms and K3 surfaces

open access: yes, 2006
We study differential equations satisfied by modular forms associated to $\Gamma_1\times\Gamma_2$, where $\Gamma_i (i=1,2)$ are genus zero subgroups of $SL_2(\mathbf R)$ commensurable with $SL_2(\mathbf Z)$, e.g., $\Gamma_0(N)$ or $\Gamma_0(N)^*$.
Yang, Yifan, Yui, Noriko
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

ON INITIAL BOUNDARY VALUE PROBLEMS FOR THE DEGENERATE 1D WAVE EQUATION

open access: yesJournal of Optimization, Differential Equations and Their Applications, 2019
Initial boundary value problems in space-time rectangle for the following linear inhomogeneous degenerate wave equation of the second order smooth coefficient function a(x) vanishes in single points of segment.
Vladimir V. Borsch
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Functional differential equations close to differential equations [PDF]

open access: yesBulletin of the American Mathematical Society, 1966
when the lag function r(t) is nearly constant for large /, and has also asked for conditions on the function r under which all solutions approach zero as t—» oo. The purpose of this announcement is to initiate a study of various stability and oscillation problems for equations with perturbed lag functions, and to suggest that a modification of the ...
openaire   +2 more sources

Arithmetic partial differential equations, I

open access: yesAdvances in Mathematics, 2010
Updated version of paper includes new results on ...
Buium, Alexandru, Simanca, Santiago R.
openaire   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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