Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Enhanced mutation strategy based differential evolution for global optimization problems. [PDF]
Mishra P, Ali M, Pooja, Islam S.
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A HyChem Model of Polyoxymethylene Dimethyl Ether 5 Optimized with a Differential Evolution Algorithm. [PDF]
Li G, Tao Y.
europepmc +1 more source
Neighborhood Adaptive Differential Evolution
openaire +3 more sources
Solution of optimal power flow with wind power uncertainty using hybridized self-adaptive differential evolution. [PDF]
Pulluri H +9 more
europepmc +1 more source
Leveraging blockchain for cybersecurity detection using hybridization of prairie dog optimization with differential evolution on internet of things environment. [PDF]
Alruwaili FF.
europepmc +1 more source
Optimizing dance motion reconstruction using a two-dimensional matrix approach with hybrid genetic and fuzzy logic differential evolution. [PDF]
Wang L, Liu Y, Geng Y, Khishe M.
europepmc +1 more source
Dynamic economic emission dispatch of combined heat and power system based on multi-objective differential evolution algorithm. [PDF]
Dong T.
europepmc +1 more source
A Differential Evolution-Based Optimized Ensemble for Balanced and Imbalanced Medical Datasets. [PDF]
Das S +3 more
europepmc +1 more source

