Results 51 to 60 of about 442,456 (299)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

DIFFERENTIAL EVOLUTION FOR OPTIMIZATION OF PID GAIN IN ELECTRICAL DISCHARGE MACHINING CONTROL SYSTEM [PDF]

open access: yes, 2012
PID controller of servo control system maintains the gap between Electrode and workpiece in Electrical Dis- charge Machining (EDM). Capability of the controller is significant since machining process is a stochastic phenomenon and physical behaviour of ...
Andromeda, Trias   +4 more
core  

Differential evolution based bi-level programming algorithm for computing normalized nash equilibrium

open access: yes, 2011
The Generalised Nash Equilibrium Problem (GNEP) is a Nash game with the distinct feature that the feasible strategy set of a player depends on the strategies chosen by all her opponents in the game.
Koh, Andrew
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

A Reward Population-Based Differential Genetic Harmony Search Algorithm

open access: yesAlgorithms, 2022
To overcome the shortcomings of the harmony search algorithm, such as its slow convergence rate and poor global search ability, a reward population-based differential genetic harmony search algorithm is proposed.
Yang Zhang, Jiacheng Li, Lei Li
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

An Approximate Optimization Method for Solving Stiff Ordinary Differential Equations With Combinational Mutation Strategy of Differential Evolution Algorithm

open access: yesMendel, 2022
This paper examines the implementation of simple combination mutation of differential evolution algorithm for solving stiff ordinary differential equations.
Werry Febrianti   +2 more
doaj   +1 more source

Making up for the deficit in a marathon run

open access: yes, 2017
To predict the final result of an athlete in a marathon run thoroughly is the eternal desire of each trainer. Usually, the achieved result is weaker than the predicted one due to the objective (e.g., environmental conditions) as well as subjective ...
Brest, Janez   +5 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Multi-Auv Distributed Task Allocation Based on the Differential Evolution Quantum Bee Colony Optimization Algorithm

open access: yesPolish Maritime Research, 2017
The multi-autonomous underwater vehicle (AUV) distributed task allocation model of a contract net, which introduces an equilibrium coefficient, has been established to solve the multi-AUV distributed task allocation problem.
Li Jianjun, Zhang Ru Bo
doaj   +1 more source

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