Results 81 to 90 of about 442,456 (299)

Differential Evoluiton - Particle Swarm Optimization [PDF]

, 2011
This paper shows the Particle Swarm Optimization algorithm with a Differential Evolution. Each candidate solution is sampled uniformly in [!5,5] D, whereDdenotes the search space dimension, and the evolution is performed with a classical PSO algorithm ...
Arteta Albert, Alberto, Gómez Blas, Nuria, Mingo López, Luis Fernando de   +2 more
core   +1 more source

A Feature-Based Analysis on the Impact of Set of Constraints for e-Constrained Differential Evolution

, 2015
Different types of evolutionary algorithms have been developed for constrained continuous optimization. We carry out a feature-based analysis of evolved constrained continuous optimization instances to understand the characteristics of constraints that ...
Neumann, FranK, Poursoltan, Shayan
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Comparison of the Asynchronous Differential Evolution and JADE Minimization Algorithms

EPJ Web of Conferences, 2016
Differential Evolution (DE) is an efficient evolutionary algorithm to solve global optimization problems. In this work we compare performance of the recently proposed Asynchronous Differential Evolution with Adaptive Correlation Matrix (ADEACM) to the ...
Zhabitsky Mikhail
doaj   +1 more source

Reduced-Order Modeling based on Approximated Lax Pairs [PDF]

, 2012
A reduced-order model algorithm, based on approximations of Lax pairs, is proposed to solve nonlinear evolution partial differential equations. Contrary to other reduced-order methods, like Proper Orthogonal Decomposition, the space where the solution is
Gerbeau, Jean-Frédéric, Lombardi, Damiano   +1 more
core   +3 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

An improved negative selection algorithm based on the hybridization of cuckoo search and differential evolution for anomaly detection [PDF]

, 2018
The biological immune system (BIS) is characterized by networks of cells, tissues, and organs communicating and working in synchronization. It also has the ability to learn, recognize, and remember, thus providing the solid foundation for the ...
Ayodele Nojeem, Lasisi
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Virtual Simulation of Integrated Circuits Combining AP with DE Algorithm

Electronics
As computers develops, virtual simulation technology becomes an important means of integrated circuit design. Therefore, based on the demand for virtual simulation of integrated circuits, a simulation method combining affinity propagation and ...
Peipei Hu
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source