Results 51 to 60 of about 537,542 (327)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Linear evasion differential game of one evader and several pursuers with integral constraints

International Journal of Game Theory, 2021
An evasion differential game of one evader and many pursuers is studied. The dynamics of state variables x1,…,xm\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy ...
G. Ibragimov, M. Ferrara, Marks Ruziboev, B. Pansera   +3 more
semanticscholar   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Optimal Co-location of Geo-satellites in the Orbital Slot of 120 Degrees East Using Differential Game Theory [PDF]

علوم، فناوری و کاربردهای فضایی
Due to the increasing demand for locating satellites in the geostationary orbit and considering the operational limitations in defining the geo-orbital slots, the use of a same location by several satellites is one of the solutions to increase the ...
fatemeh amozegary, Amirreza Kosari, Mahdi Fakoor   +2 more
doaj   +1 more source

Differential Game Approach for Attack-Defense Strategy Analysis in Internet of Things Networks

IEEE Internet of Things Journal, 2022
Internet of Things (IoT) is vulnerable to various cyber attacks due to the massive deployment of IoT devices and the openness of wireless environments.
Huici Wu, Q. Gao, Xiaofeng Tao, Ning Zhang, Dajiang Chen, Zhu Han   +5 more
semanticscholar   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Cooperative Hunting Method for Multiple ASVs Using Differential Games Based on Escape Angle

水下无人系统学报
In the scenario where multi-autonomous surface vehicles(ASVs) round up an actively escaped adversarial target, a game model of the multi-ASV cooperative hunting problem was established using differential game theory.
Huizhen YANG, Jianguo LI, Tianyu WU, Zijiang WANG, Jun YANG   +4 more
doaj   +1 more source

Coevolution of Artificial Agents Using Evolutionary Computation in Bargaining Game

Advances in Multimedia, 2015
Analysis of bargaining game using evolutionary computation is essential issue in the field of game theory. This paper investigates the interaction and coevolutionary process among heterogeneous artificial agents using evolutionary computation (EC) in the
Sangwook Lee
doaj   +1 more source

Energy-Efficient Resource Management in Ultra Dense Small Cell Networks: A Mean-Field Approach

, 2015
In this paper, a novel approach for joint power control and user scheduling is proposed for optimizing energy efficiency (EE), in terms of bits per unit power, in ultra dense small cell networks (UDNs). To address this problem, a dynamic stochastic game (
Bennis, Mehdi, Debbah, Mérouane, Latva-aho, Matti, Saad, Walid, Samarakoon, Sumudu   +4 more
core   +3 more sources