Results 41 to 50 of about 741,871 (299)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A primer on exterior differential calculus [PDF]
A pedagogical application-oriented introduction to the calculus of exterior differential forms on differential manifolds is presented. Stokes' theorem, the Lie derivative, linear connections and their curvature, torsion and non-metricity are discussed.
Burton D.A.
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Fermions, differential forms and doubled geometry
We show that all fermions of one generation of the Pati–Salam version of the Standard Model (SM) can be elegantly described by a single fixed parity (say even) inhomogeneous real-valued differential form in seven dimensions.
Kirill Krasnov
doaj +1 more source
Analytical ruled surfaces and their complete classification
The aim of the work - to give the possibility to expand mind of designers and architects projecting structures in the form of traditional and non-canonical ruled surfaces.
Sergey N. Krivoshapko
doaj +1 more source
Differential Algebras in Non-Commutative Geometry
We discuss the differential algebras used in Connes' approach to Yang-Mills theories with spontaneous symmetry breaking. These differential algebras generated by algebras of the form functions $\otimes$ matrix are shown to be skew tensorproducts of ...
Chamseddine +19 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Evaluation of Linearization Methods for Control of the Pendubot
The aim of this paper is to test the usefulness of a new approach based on partial feedback linearization to control the Pendubot. The control problem stated in the article is to stabilize the Pendubot in the upright position.
Paweł Parulski +2 more
doaj +1 more source
Differential Geometry of the q-plane
Hopf algebra structure on the differential algebra of the extended $q$-plane is defined. An algebra of forms which is obtained from the generators of the extended $q$-plane is introduced and its Hopf algebra structure is given.Comment: 9 ...
Reshetikhin N. Y. +2 more
core +1 more source

