Results 51 to 60 of about 746,310 (284)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

On organizing principles of Discrete Differential Geometry. Geometry of spheres

, 2006
Discrete differential geometry aims to develop discrete equivalents of the geometric notions and methods of classical differential geometry. In this survey we discuss the following two fundamental Discretization Principles: the transformation group ...
Bobenko, Alexander I., Suris, Yuri B.
core   +2 more sources

Extrinsic Geometry and Linear Differential Equations

, 2020
We give a unified method for the general equivalence problem of extrinsic geometry, on the basis of our formulation of a general extrinsic geometry as that of an osculating map $\varphi\colon (M,\mathfrak f) \to L/L^0 \subset \operatorname{Flag}(V,\phi)$
Doubrov, Boris, Machida, Yoshinori, Morimoto, Tohru   +2 more
core   +1 more source

Tangent Categories from the Coalgebras of Differential Categories [PDF]

, 2019
Following the pattern from linear logic, the coKleisli category of a differential category is a Cartesian differential category. What then is the coEilenberg-Moore category of a differential category? The answer is a tangent category!
Cockett, Robin, Lemay, Jean-Simon Pacaud, Lucyshyn-Wright, Rory B. B.   +2 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Stability of an additive-quadratic functional equation in modular spaces

Open Mathematics
Using the direct method, we prove the Hyers-Ulam-Rassias stability of the following functional equation: ϕ(x+y,z+w)+ϕ(x−y,z−w)−2ϕ(x,z)−2ϕ(x,w)=0\phi \left(x+y,z+w)+\phi \left(x-y,z-w)-2\phi \left(x,z)-2\phi \left(x,w)=0 in ρ\rho -complete convex modular ...
Baza Abderrahman, Rossafi Mohamed, Park Choonkil, Donganont Mana   +3 more
doaj   +1 more source

DeepDefend: A comprehensive framework for DDoS attack detection and prevention in cloud computing

Journal of King Saud University: Computer and Information Sciences
DeepDefend is an advanced framework for real-time detection and prevention of DDoS attacks in cloud environments. It employs deep learning techniques, notably CNN-LSTM-Transformer networks, to predict network traffic entropy and detect potential attacks.
Mohamed Ouhssini, Karim Afdel, Elhafed Agherrabi, Mohamed Akouhar, Abdallah Abarda   +4 more
doaj   +1 more source

A visualization of null geodesics for the bonnor massive dipole

Revista de Matemática: Teoría y Aplicaciones, 2015
In this work we simulate null geodesics for the Bonnor massive dipole metric by implementing a symbolic-numerical algorithm in Sage and Python. This program is also capable of visualizing in 3D, in principle, the geodesics for any given metric. Geodesics
G. Andree Oliva Mercado, Javier Bonatti González, Iván Cordero García, Francisco Frutos Alfaro   +3 more
doaj   +1 more source

Examples of derivation-based differential calculi related to noncommutative gauge theories

, 2008
Some derivation-based differential calculi which have been used to construct models of noncommutative gauge theories are presented and commented. Some comparisons between them are made.Comment: 22 pages, conference given at the "International Workshop in
Chari V., Connes A., Connes A., Dubois-Violette M., Dubois-Violette M., Dubois-Violette M., Gracia-Bondia J. M., Kerner R., Kerner R., Masson T., T. MASSON, Wallet J.-C.   +11 more
core   +4 more sources

Geometry of Differential Space

The Annals of Probability, 1973
The purpose of this paper is to explain why it is fruitful to think of Wiener space as an infinite--dimensional sphere of radius $\infty\frac{1}{2}$. The idea goes back to Levy and Wiener and has recently been employed to advantage by Hida; Hida, Kubo, Nomoto and Yosizawa; Kono; Orihara and Umemura; their results will be reported upon below.
openaire   +3 more sources