Results 41 to 50 of about 746,310 (284)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Analytical ruled surfaces and their complete classification

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2020
The aim of the work - to give the possibility to expand mind of designers and architects projecting structures in the form of traditional and non-canonical ruled surfaces.
Sergey N. Krivoshapko
doaj   +1 more source

Differential Geometry of Toda Systems

open access: yes, 1993
In the present paper we give a differential geometry formulation of the basic dynamical principle of the group--algebraic approach \cite{LeS92} --- the grading condition --- in terms of some holomorphic distributions on flag manifolds associated with the
Razumov, A. V., Saveliev, M. V.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Quantum Field Theory and Differential Geometry

open access: yes, 2008
We introduce the historical development and physical idea behind topological Yang-Mills theory and explain how a physical framework describing subatomic physics can be used as a tool to study differential geometry.
Freedman M.   +5 more
core   +1 more source

Canonical differential geometry of string backgrounds [PDF]

open access: yes, 2006
String backgrounds and D-branes do not possess the structure of Lorentzian manifolds, but that of manifolds with area metric. Area metric geometry is a true generalization of metric geometry, which in particular may accommodate a B-field.
A. Fotopoulos   +15 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Feature Lines for Illustrating Medical Surface Models: Mathematical Background and Survey

open access: yes, 2015
This paper provides a tutorial and survey for a specific kind of illustrative visualization technique: feature lines. We examine different feature line methods.
A. Chu   +24 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Evaluation of Linearization Methods for Control of the Pendubot

open access: yesApplied Sciences, 2021
The aim of this paper is to test the usefulness of a new approach based on partial feedback linearization to control the Pendubot. The control problem stated in the article is to stabilize the Pendubot in the upright position.
Paweł Parulski   +2 more
doaj   +1 more source

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