Results 51 to 60 of about 84,589 (290)

Closed, Two Dimensional Surface Dynamics

open access: yesFrontiers in Physics, 2018
We present dynamic equations for two dimensional closed surfaces and analytically solve it for some simplified cases. We derive final equations for surface normal motions by two different ways. The solution of the equations of motions in normal direction
David V. Svintradze
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

A primer on exterior differential calculus [PDF]

open access: yesTheoretical and Applied Mechanics, 2003
A pedagogical application-oriented introduction to the cal­culus of exterior differential forms on differential manifolds is presented. Stokes' theorem, the Lie derivative, linear con­nections and their curvature, torsion and non-metricity are discussed.
Burton D.A.
doaj   +1 more source

Functional Segmentation for Preoperative Liver Resection Based on Hepatic Vascular Networks

open access: yesIEEE Access, 2021
Successful liver resection relies on accurate estimation of future liver remnant volume (FLRV). According to Couinaud's scheme, a liver is composed of eight functionally independent segments, each of which has its own vascular in- and out-flow tracks ...
Doan Cong Le   +3 more
doaj   +1 more source

Differentiators and the geometry of polynomials

open access: yesJournal of Mathematical Analysis and Applications, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

Structural Reliability and Optimization Using Differential Geometric Approaches

open access: yesIraqi Journal for Computer Science and Mathematics
This study investigates how differential geometry ideas can be used to effectively carry out structural optimization and reliability analysis. Strong mathematical representations and methods for examining intricate surfaces and forms are provided by ...
Saad Abbas Abed   +4 more
doaj   +1 more source

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