Results 61 to 70 of about 4,106,348 (385)
FEBS Letters, EarlyView.We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin +2 more
wiley +1 more source
Functional Segmentation for Preoperative Liver Resection Based on Hepatic Vascular Networks
IEEE Access, 2021 Successful liver resection relies on accurate estimation of future liver remnant volume (FLRV). According to Couinaud's scheme, a liver is composed of eight functionally independent segments, each of which has its own vascular in- and out-flow tracks ...
Doan Cong Le +3 more
doaj +1 more source
Cubic Differentials in the Differential Geometry of Surfaces [PDF]
, 2016 We discuss the local differential geometry of convex affine spheres in $\re^3$ and of minimal Lagrangian surfaces in Hermitian symmetric spaces. In each case, there is a natural metric and cubic differential holomorphic with respect to the induced conformal structure: these data come from the Blaschke metric and Pick form for the affine spheres and ...
Loftin, John, McIntosh, Ian
openaire +3 more sources
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Closed, Two Dimensional Surface Dynamics
Frontiers in Physics, 2018 We present dynamic equations for two dimensional closed surfaces and analytically solve it for some simplified cases. We derive final equations for surface normal motions by two different ways. The solution of the equations of motions in normal direction
David V. Svintradze
doaj +1 more source
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Molecular Oncology, EarlyView.Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler +12 more
wiley +1 more source
Geometrical modeling and numerical analysis of edge dislocation
Nihon Kikai Gakkai ronbunshu, 2021 In this study, we conduct modeling and numerical analysis of a straight edge dislocation in a three-dimensional geometrically nonlinear elastic medium.
Shunsuke KOBAYASHI, Ryuichi TARUMI
doaj +1 more source
Differential Algebras in Non-Commutative Geometry
, 1993 We discuss the differential algebras used in Connes' approach to Yang-Mills theories with spontaneous symmetry breaking. These differential algebras generated by algebras of the form functions $\otimes$ matrix are shown to be skew tensorproducts of ...
Chamseddine +19 more
core +1 more source
Nonsmooth differential geometry - An approach tailored for spaces with Ricci curvature bounded from below [PDF]
, 2014 We discuss in which sense general metric measure spaces possess a first order differential structure. Building on this, we then see that on spaces with Ricci curvature bounded from below a second order calculus can be developed, permitting to define ...
N. Gigli
semanticscholar +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source