Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014 Purpose: Current study investigated whether the measurement tools utilized during medical faculty preclinical period to form the basis of pass-fail decisions taken for students included Differential Item Functioning for foreign and Turkish students ...
Huseyin Selvi +2 more
doaj
Erratum: Differential item functioning of the CESD-R and GAD-7 in African and white working adults
, 2021 Carolina Henn, Brandon Morgan
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Differential Item Functioning of the test subjects in the English language course administered to students of Mu'tah University [PDF]
, 2018 Ahmed J. Matarneh, Boushra M. Oalla
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FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
An explanatory differential item functioning (DIF) model by the WinBUG 1.4 [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2007 This study proposed a multilevel logistic regression model to evaluate a source of DIF. The model accounts for the three levels nested structure of the data and combines results of logistic regression analysesto identify level-3 unit characteristic ...
Fred W. Huffer +2 more
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Differential Item Functioning of Verbal Ability Test in the Gulf Multiple Mental Abilities Scale by Mental-Haenszel and Likelihood Ratio Test [PDF]
, 2023 Mohammed Al Ajmi +3 more
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Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source