Results 51 to 60 of about 323,428 (284)

Tension mediated nonlinear coupling between orthogonal mechanical modes of nanowire resonators

, 2018
We study the nonlinear coupling between orthogonal flexural modes of doubly clamped InAs nanowire resonators. The two orthogonal modes are formed by the symmetry breaking and lifting of degeneracy of the fundamental mode.
Bhushan, Anand, Deshmukh, Mandar M., Mathew, John P.   +2 more
core   +1 more source

Kinematic calibration of Orthoglide-type mechanisms from observation of parallel leg motions [PDF]

, 2009
The paper proposes a new calibration method for parallel manipulators that allows efficient identification of the joint offsets using observations of the manipulator leg parallelism with respect to the base surface.
Chablat, Damien, Pashkevich, Anatoly, Wenger, Philippe   +2 more
core   +6 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Linear and nonlinear capacitive coupling of electro-opto-mechanical photonic crystal cavities [PDF]

, 2014
We fabricate and characterize a microscale silicon electro-opto-mechanical system whose mechanical motion is coupled capacitively to an electrical circuit and optically via radiation pressure to a photonic crystal cavity.
Fink, Johannes M., Hill, Jeff T., Lei, Chan U., Painter, Oskar, Pitanti, Alessandro, Safavi-Naeini, Amir H., Tredicucci, Alessandro   +6 more
core   +1 more source

A Mechanical–Electrical Model to Describe the Negative Differential Resistance in Membranotronic Devices

physica status solidi (RRL) – Rapid Research Letters
Membranotronic devices are artificial neural membranes mimicing the functionality of biological neural networks. These devices rely on the emergence of negative differential resistance (NDR). A minimalistic physical model for membranotronic devices capable of generating NDR is presented.
Max Huber, Jörg Schuster, Oliver G. Schmidt, Harald Kuhn, Daniil Karnaushenko   +4 more
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Influence of System and Actuator Nonlinearities on the Dynamics of Ring-Type MEMS Gyroscopes

Vibration, 2021
This study investigates the nonlinear dynamic response behavior of a rotating ring that forms an essential element of MEMS (Micro Electro Mechanical Systems) ring-based vibratory gyroscopes that utilize oscillatory nonlinear electrostatic forces.
Ibrahim F. Gebrel, Samuel F. Asokanthan
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Analysis of main dynamic parameters of split power transmission [PDF]

Transport, 2008
The review carried out had shown one basic approach of split power transmission to the organization of drive which is applied to stepless transmissions of tractors and parallel hybrid cars.
Algirdas Janulevičius, Kazimieras Giedra   +1 more
doaj   +1 more source

Respiratory pressure and flow data collection device providing a framework for closed-loop mechanical ventilation

HardwareX
This article details a pressure and flow sensor system device which enables a framework for the research and development of personalized mechanical ventilator support in a closed-loop or semi-closed-loop control system, where the measurements from this ...
Samuel Hastings, Jacob Mildenhall, Kayla Sinclair, Ella F.S. Guy, Jaimey A. Clifton, Jordan F. Hill, Yunpeng Su, J. Geoffrey Chase   +7 more
doaj   +1 more source