Results 61 to 70 of about 5,234,588 (286)

A device for testing the electronic and mechanical properties of conducting polymers with electron paramagnetic resonance spectroscopy [PDF]

, 2004
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2004.Includes bibliographical references (leaf 35).Conducting polymers have the potential to serve the technical and commercial communities with novel actuators ...
Powley, Nicholas R. (Nicholas Ransom), 1982-
core  

Geometric Dimensioning and Tolerancing. Method Based on the Assembly Diagram of a Mechanical Device. Case Study of a V-axis Positioning Device [PDF]

[EN] This paper proposes a methodology, based on the use of the assembly diagram of a mechanical device, to determine the geometrical and dimensional conditions of the parts that directly influence the functional conditions of the mechanical device to ...
Montalvá-Colomer, Jorge, Brusola Simón, Fernando, Defez Garcia, Beatriz, Tortajada Montañana, Ignacio, Roca, Francisco, Rubió Sanvalero, Carlos Miguel   +5 more
core   +1 more source

Behaviour study of an eccentric pulley transmission system using systemic methods

Dyna, 2019
This paper describes a case study carried out on the behaviour of an eccentric pulley transmission system housed in a manually operated abdominal-intestinal assistant device for human use.
Iñaki Esnal Angulo, Bernabé Hernandis Ortuño   +1 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Negative differential resistance in memristive systems: historical evolution, mechanisms and neuromorphic applications of niobium oxide devices

Nanoscale
Elucidates diverse NDR mechanisms, modulation strategies, and historical evolution. Comprehensive review of NDR and its application in niobium oxide systems. Offers insights into NDR-memristor synergy for neuromorphic and low-power circuits.
Hongyi Lu, Shiyu Xie, Weijian Zhang, Yue Chen, Jianming Tao, Chinmayee Mandar Mhaskar, Ayan Roy Chaudhuri, Yingbin Lin, Jiaxin Li, Sanjay Mathur, Zhigao Huang   +10 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

INFLUENCE OF THE TIME OF DISINHIBITION TO TRANSIENTS AND WEAR OF THE FRICTION LININGS IN AN ASYNCHRONOUS MOTOR

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2016
Time and the stopping distance of the electric drive with frequent starting-and-braking modes that contain embedded asynchronous motor with a recessed combined braking device depend on the moment of an electromagnet disinhibition.
V. V. Solencov, V. V. Brel
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Biventricular Mechanical Circulatory Support Does Not Prevent Delayed Myocardial Ventricular Rupture following Myocardial Infarction

Case Reports in Cardiology, 2013
Cardiogenic shock and myocardial rupture can complicate an acute myocardial infarction (AMI). A case is reported in which a 58-year-old male with an acute inferior myocardial infarction required placement of biventricular assist device for hemodynamic ...
Yazhini Ravi, Emily P. Sudhakar, Pratima Nayak, Chittoor B. Sai-Sudhakar, Konstantinos Dean Boudoulas   +4 more
doaj   +1 more source