Results 71 to 80 of about 323,428 (284)

Coulomb Blockade in a Coupled Nanomechanical Electron Shuttle

, 2012
We demonstrate single electron shuttling through two coupled nanomechanical pendula. The pendula are realized as nanopillars etched out of the semiconductor substrate. Coulomb blockade is found at room temperature, allowing metrological applications.
Ahn K.-H., Azuma Y., Azuma. Y., Blencowe M., Blick R. H., Chang P., Chulki Kim, Cleland A. N., Craighead H. G., Erbe A., Geerligs L. J., Gorelik L. Y., Grabert H., Han K. H., Holleitner A. W., Kim C., Kim H. S., Kim H. S., Koenig D., Leuzzi L., Marta Prada, Robert H. Blick, Roukes M. L., Scheible D. V., Scheible D. V., Shekhter R. I., Tinkham M. I., Weiss C., Weldon J. A., Wilkins R.   +29 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Probing the charge of a quantum dot with a nanomechanical resonator

, 2012
We have used the mechanical motion of a carbon nanotube (CNT) as a probe of the average charge on a quantum dot. Variations of the resonance frequency and the quality factor are determined by the change in average charge on the quantum dot during a ...
A. Taspinar, B. H. Schneider, G. A. Steele, G. Labadze, H. B. Meerwaldt, H. B. Meerwaldt, H. S. J. van der Zant, R. Lifshitz, Ya. M. Blanter   +8 more
core   +2 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

INFLUENCE OF THE TIME OF DISINHIBITION TO TRANSIENTS AND WEAR OF THE FRICTION LININGS IN AN ASYNCHRONOUS MOTOR

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2016
Time and the stopping distance of the electric drive with frequent starting-and-braking modes that contain embedded asynchronous motor with a recessed combined braking device depend on the moment of an electromagnet disinhibition.
V. V. Solencov, V. V. Brel
doaj   +1 more source

Low Power Resonant Optical Excitation of an Optomechanical Cavity

, 2010
We demonstrate the actuation of a double beam opto-mechanical cavity with a sinusoidally varying optical input power. We observe the driven mechanical motion with only 200 nW coupled to the optical cavity mode.
Altug, Arka Majumdar, Armand Rundquist, Eichenfield, Eichenfield, Eichenfield, Englund, Jelena Vučković, Kippenberg, Kippenberg, Kippenberg, Li, Li, Notomi, Pernice, Povinelli, Povinelli, Quan, Roels, Safavi-Naeini, Schliesser, Van Thourhout, Wiederhecker, Yiyang Gong   +23 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Biventricular Mechanical Circulatory Support Does Not Prevent Delayed Myocardial Ventricular Rupture following Myocardial Infarction

Case Reports in Cardiology, 2013
Cardiogenic shock and myocardial rupture can complicate an acute myocardial infarction (AMI). A case is reported in which a 58-year-old male with an acute inferior myocardial infarction required placement of biventricular assist device for hemodynamic ...
Yazhini Ravi, Emily P. Sudhakar, Pratima Nayak, Chittoor B. Sai-Sudhakar, Konstantinos Dean Boudoulas   +4 more
doaj   +1 more source

Optical read out and feedback cooling of a nanostring optomechanical cavity [PDF]

, 2015
Optical measurement of the motion of a 940 kHz mechanical resonance of a silicon nitride nanostring resonator is demonstrated with a read out noise imprecision reaching 37 dB below that of the resonator's zero-point fluctuations. Via intensity modulation
Blasius, Tim D., Krause, Alex G., Painter, Oskar   +2 more
core   +1 more source