Results 131 to 140 of about 4,425,780 (307)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Octagonal large-mode-area leakage channel fiber with reduced bending loss

, 2010
We investigate a novel design for high-power large-mode-area leakage channel fibers (LCFs) with a single octagonal dual-diameter air-hole ring encircling a nine-cell pure-silica core, having a tenfold differential mode loss and increased resistance to ...
Lorenzo Rosa (4053517), Debashri Ghosh (19123162), Stefano Selleri (17510241), Mrinmay Pal (19104707), Annamaria Cucinotta (12893612), Shyamal Bhadra (19123165), Kunimasa Saitoh (3972053), Luca Vincetti (14388753), Federica Poli (3315855), Masanori Koshiba (3972056), Mukul Paul (19123168)   +10 more
core   +1 more source

Polarization mode dispersion reduction in spun silica holey fibres

We report the fabrication of a spun holey optical fibre. Our experiments show that the complex air/glass transverse structure can be retained when the preform is spun during the fibre drawing process.
Petrovich, M.N., Fuochi, M., Baggett, J.C., Richardson, D.J., Monro, T.M., Hayes, J.R.   +5 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Comparison of the differential mode against the coherent mode in G3-PLC [PDF]

, 2014
In 2013, the updated version of G3-PLC was re¬leased. This new version proposes the possibility to choose between a differential and a coherent mode for the physical layer. In [4], PRIME and the differential mode of G3-PLC physical layer are discussed to
Van den Bergh, Samuel, Reynders, Brecht, Van Lil, Emmanuel, Pollin, Sofie   +3 more
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Flexible Common-Mode Voltage Modulation Strategy for Differential Boost Inverters

Energies
Photovoltaic power generation and energy storage technology are current hotspots in the clean energy industry. As a core piece of equipment, an inverter is subjected to higher demands for its voltage regulation range and output performance.
Zhaozhe Deng, Hao Qin, Wenbo Zhu, Qi Qiu, Yan Deng, Xiangning He   +5 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Automatic Differentiation: Inverse Accumulation Mode

Presented at AD2024, https://www.autodiff.org/ad24/, to appear in ...
Barak A. Pearlmutter, Jeffrey Mark Siskind   +1 more
openaire   +2 more sources