Results 121 to 130 of about 4,425,780 (307)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Reconfigurable modal gain control of a few-mode EDFA supporting six spatial modes

, 2014
We experimentally demonstrate an inline few-mode erbium doped fiber amplifier supporting six spatial modes with reconfigurable differential gain control and excellent gain flatness obtained through mode-selective bidirectional pumping of a custom fiber ...
Alam, S.U., Corbett, B., Jung, Y., Kang, Q., O'Callaghan, J., Richardson, D.J., O'Callagham, J., Poletti, F., Sahu, J.K.   +8 more
core   +1 more source

CM-YOLO: A Multimodal PCB Defect Detection Method Based on Cross-Modal Feature Fusion

Sensors
By integrating information from RGB images and depth images, the feature perception capability of a defect detection algorithm can be enhanced, making it more robust and reliable in detecting subtle defects on printed circuit boards.
Haowen Lan, Jiaxiang Luo, Hualiang Zhang, Xu Yan   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Circularly-Polarized Differential Antenna Array Fed by Single-Ended-to-Balanced Power Dividers with High Common-Mode Rejection

, 2020
This paper presents a differential feeding network comprising of a new type of single-ended-to-balanced power dividers with high level of common-mode rejection.
Guo, YJ, Zhu, H, He Zhu, Y. Jay Guo
core   +1 more source

Three-Sensor Current Control Strategy for Zero Phase-Shift Dual Three-Phase SPMSM Drives

IEEE Access
This paper proposes a three-sensor current control strategy for an axial-flux zero phase-shift dual three-phase surface-mounted permanent-magnet synchronous motor drive.
Daeyeon Hwang, Pooreum Jang, Bon-Gwan Gu
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Generation of common mode in non-uniform differential interconnections

, 2017
This work investigates the mechanism of generation of undesired common-mode (CM) currents in differential-line interconnects with slight non-uniformity owing to imperfect production process.
Grassi, F., Vande Ginste D, WU, XINGLONG, Liu, X., Pignari, S. A., Ginste, D. Vande, Liu X, P. Manfredi, Vande Ginste, Dries, S. A. Pignari, F. Grassi, Manfredi P, Sun J, Pignari SA, Wu X, X. Wu, Sun, J., X. Liu, Manfredi, Paolo, J. Sun, D. Vande Ginste, Wu, X., Manfredi, P., Grassi F, LIU, XIAOKANG   +24 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source