Results 51 to 60 of about 86,356 (264)

Neutral Operator and Neutral Differential Equation

open access: yesAbstract and Applied Analysis, 2011
In this paper, we discuss the properties of the neutral operator (Ax)(t)=x(t)−cx(t−δ(t)), and by applying coincidence degree theory and fixed point index theory, we obtain sufficient conditions for the existence, multiplicity, and nonexistence of ...
Jingli Ren, Zhibo Cheng, Stefan Siegmund
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Selfadjoint Singular Quasi-Differential Operators for First Order

open access: yesHittite Journal of Science and Engineering, 2019
I n this work, using the Calkin-Gorbachuk method firstly all selfadjoint extensions of the minimal operator generated by first order linear singular quasi-differential expression in the weighted Hilbert space of vector-functions on right semi-axis have ...
Pembe Ipek Al, Zameddin Ismailov
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

On the solvability of a fourth order operator differential equations

open access: yesElectronic Journal of Differential Equations, 2007
We establish sufficient conditions for the solvability of a fourth order operator differential equation. These conditions are expressed in terms of operator coefficients.
Ahmed Nouar
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

On New p-Valent Meromorphic Function Involving Certain Differential and Integral Operators

open access: yesAbstract and Applied Analysis, 2014
We define new subclasses of meromorphic p-valent functions by using certain differential operator. Combining the differential operator and certain integral operator, we introduce a general p-valent meromorphic function.
Aabed Mohammed, Maslina Darus
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

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