Results 71 to 80 of about 100,397 (305)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Discrete spectrum and principal functions of non-selfadjoint differential operator [PDF]

open access: yes, 1999
summary:In this article, we consider the operator $L$ defined by the differential expression \[ \ell (y)=-y^{\prime \prime }+q(x) y ,\quad - \infty 0 \] holds.
Bairamov, Elgiz   +1 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Existence of solutions to fractional differential inclusions with p-laplacian operator

open access: yes, 2014
 In this article, we are prove the existence of solutions for three-point fractional differential inclusions with p-Laplacian operator. We use fixed point theory for set valued upper semi-continuous maps for obtaining the solutions.
Topal, F.S., Yantir, A.
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Schrödinger operators with δ and δ′-potentials supported on hypersurfaces

open access: yes, 2013
Self-adjoint Schrödinger operators with δ and δ′-potentials supported on a smooth compact hypersurface are defined explicitly via boundary conditions.
Lotoreichik, Vladimir   +2 more
core   +1 more source

Selfadjoint Singular Quasi-Differential Operators for First Order

open access: yesHittite Journal of Science and Engineering, 2019
I n this work, using the Calkin-Gorbachuk method firstly all selfadjoint extensions of the minimal operator generated by first order linear singular quasi-differential expression in the weighted Hilbert space of vector-functions on right semi-axis have ...
Pembe Ipek Al, Zameddin Ismailov
doaj   +1 more source

First Integrals of Differential Operators from SL(2,) Symmetries

open access: yesMathematics, 2020
The construction of first integrals for SL(2,R)-invariant nth-order ordinary differential equations is a non-trivial problem due to the nonsolvability of the underlying symmetry algebra sl(2,R).
Paola Morando   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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