Results 51 to 60 of about 1,985,807 (243)
On the representation of the Radon-Kipriyanov transform by the Riesz potential
Современная математика: Фундаментальные направленияIn this paper, a representation of the Radon-Kipriyanov transform by the classical Riesz potential is obtained. Based on the application of the Radon-Kipriyanov transform to a singular partial differential operator, a formula for transformation of a ...
L. N. Lyakhov +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Selfadjoint Singular Quasi-Differential Operators for First Order
Hittite Journal of Science and Engineering, 2019 I n this work, using the Calkin-Gorbachuk method firstly all selfadjoint extensions of the minimal operator generated by first order linear singular quasi-differential expression in the weighted Hilbert space of vector-functions on right semi-axis have ...
Pembe Ipek Al, Zameddin Ismailov
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First Integrals of Differential Operators from SL(2,ℝ) Symmetries
Mathematics, 2020 The construction of first integrals for SL(2,R)-invariant nth-order ordinary differential equations is a non-trivial problem due to the nonsolvability of the underlying symmetry algebra sl(2,R).
Paola Morando +2 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
On Some Aspects of the Differential Operator [PDF]
, 2005 The Differential Operator D is a linear operator from C1[0,1] onto C[0,1]. Its domain C1[0,1] is thoroughly studied as a meager subspace of C[0,1]. This is analogous to the status of the set of all rational numbers Q in the set of the real numbers R.
Mathew, Panakkal Jesu
core +1 more source
Determining the differential operator boundary value problems on graphs
Data Analytics and Applied MathematicsThe behaviour of functions on graph structures is studied mathematically in the context of differential operator boundary value issues on graphs. The finding of differential operators for graph boundary value issues is the focus of this abstract.
Feroz Sheakib +2 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source