Results 61 to 70 of about 2,015,390 (247)

Approximate diagonalization of variable-coefficient differential operators through similarity transformations [PDF]

, 2012
Approaches to approximate diagonalization of variable-coefficient differential operators using similarity transformations are presented. These diagonalization techniques are inspired by the interpretation of the Uncertainty Principle by Fefferman, known ...
Lambers, James V.
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Maths transformations

, 2012
A simple presentation on maths transformations by South Devon College.
South Devon College
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Backlund transformations for many-body systems related to KdV [PDF]

, 1999
We present Backlund transformations (BTs) with parameter for certain classical integrable n-body systems, namely the many-body generalised Henon-Heiles, Garnier and Neumann systems.
Kuznetsov, Vadim B., Ragnisco, Orlando, Hone ANW, Hone, Andrew N.W., Kuznetsov VB   +4 more
core   +1 more source

Preparation of Rotenone Derivatives and in Vitro Analysis of Their Antimalarial, Antileishmanial and Selective Cytotoxic Activities

Molecules, 2014
Six derivatives of the known biopesticide rotenone were prepared by several chemical transformations. Rotenone and its derivatives showed differential in vitro antiparasitic activity and selective cytotoxicity.
Yulieth Upegui, Juan F. Gil, Wiston Quiñones, Fernando Torres, Gustavo Escobar, Sara M. Robledo, Fernando Echeverri   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

B\"{a}cklund transformations as integrable discretization. The geometric approach [PDF]

Open Communications in Nonlinear Mathematical Physics
We present interpretation of known results in the theory of discrete asymptotic and discrete conjugate nets from the "discretization by B\"{a}cklund transformations" point of view.
Adam Doliwa
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

On differential transformations between Cartesian and curvilinear (geodetic) coordinates [PDF]

, 1976
Differential transformations are developed between Cartesian and curvilinear orthogonal coordinates. Only matrix algebra is used for the presentation of the basic concepts.
Soler, T.
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