Results 161 to 170 of about 3,459,071 (296)

Institute on Community Integration Annual Report: 2007-08

, 2008
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Center for Excellence in Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Genomics and Multi-Omics to Guide Clinical Management in Thyroid Cancer. [PDF]

Int J Mol Sci
Dhieb D, Bastaki K.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Institute on Community Integration Annual Report: 1994-95

, 1995
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Affiliated Program on Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Decoding Cervical Neuroendocrine Carcinoma: A Practical Review of Diagnostic Pitfalls, Differential Diagnosis and Molecular Insights. [PDF]

Diagnostics (Basel)
Onofrei Popa A, Gurau G, Patrichi G, Gurau AM, Mehedinti RC, Satala CB.   +5 more
europepmc   +1 more source

Uganda's Mandatory Newborn Sickle Cell Disease Screening Programme: Translating a Decade of Evidence into Differentiated Implementation. [PDF]

Pediatric Health Med Ther
Jonani B, Nakawuka B, Ssebunya E, Kwizera R, Bongomin F, Mboowa G.   +5 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Role-Differentiated AI Competencies and Curriculum Implications for Health Professions Education: Qualitative Study. [PDF]

JMIR Med Educ
Park Y, Han Y, Kim H, Ahn S, Kron FW, Lee J.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Capsid stabilization reprograms the nuclear fate of the HIV genome. [PDF]

Sci Adv
Mourer T, Harastani M, Cuche C, Perez-Lopez JI, Tornambe S, Tachon S, Corre G, Maristany MJ, Tinevez JY, Gazi A, Poletti V, Collepardo-Guevara R, Sartori-Rupp A, Di Nunzio F.   +13 more
europepmc   +1 more source