Results 221 to 230 of about 3,595,874 (291)

Capsid stabilization reprograms the nuclear fate of the HIV genome. [PDF]

Sci Adv
Mourer T, Harastani M, Cuche C, Perez-Lopez JI, Tornambe S, Tachon S, Corre G, Maristany MJ, Tinevez JY, Gazi A, Poletti V, Collepardo-Guevara R, Sartori-Rupp A, Di Nunzio F.   +13 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Targeted insertion of partial <i>CFTR</i> cDNA replicates native <i>CFTR</i> expression with restored channel function in CF airway epithelium. [PDF]

Mol Ther Nucleic Acids
Barillà C, Suzuki S, Park SH, Nalluri D, Wen H, Hanafy MA, Betancourth D, Umrigar A, Leir SH, Lovrenert K, Sivachenko A, Tabak B, Liu Z, Zhao R, Valley HC, Rab A, Sorscher EJ, Solomon GM, Mense M, Carulli JP, Harris A, Bao G, Davis BR.   +22 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

JAK-STAT Signaling: Mechanisms and Therapeutics in Stem Cell Biology. [PDF]

Int J Mol Sci
Li WX.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Pancreatic Collision Tumor Composed of Solid Pseudopapillary Neoplasm and Well-Differentiated Neuroendocrine Tumor: Diagnostic Challenges and Classification Considerations. [PDF]

Cureus
Valentin Lopez J, Jiang N, Cartwright D, Amin K, Mogrovejo DO, Elbaz Younes I, Schat R, Jensen E, Park BU.   +8 more
europepmc   +1 more source

Decoding Skeletal Biology Through Transcriptomics: Insights from Bulk, Single-Cell, Spatial, and Multi-Omics Approaches. [PDF]

Int J Mol Sci
Ali Z, Alqudah AM, Soubra L, Cugno C, Rahman MM.   +4 more
europepmc   +1 more source