Results 71 to 80 of about 602,927 (312)

CSA Practices for Sustainable Cocoa Farming Systems [PDF]

open access: yes, 2020
Climate change will shape the future production of cocoa and requires mutual cooperation amongst sector stakeholders to tailor responses to its differentiated impacts.
Nguyen Duy Nhiem   +3 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Economic integration, intensity of competition and R&D incentives

open access: yes, 1999
A two-country differentiated duopoly model is set out in which economic integration increases firms' incentives to invest in R&D, purely through the effect of increased intensity of competition between firms.
McVicar, Duncan
core  

Generalized Galileons: All scalar models whose curved background extensions maintain second-order field equations and stress tensors [PDF]

open access: yes, 2009
We extend to curved backgrounds all flat-space scalar field models that obey purely second-order equations, while maintaining their second-order dependence on both field and metric.
Deffayet, C.   +2 more
core   +4 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Vertical Integration versus Vertical Separation: An Equilibrium Model [PDF]

open access: yes
. In this paper, the role of strategic forces in vertical relationships is examined. Using a simple model of differentiated products with symmetric demands and costs, the Perfect equilibrium to a vertical integration-vertical separation game between ...
Cyrenne, Philippe
core   +1 more source

Polish Interstate Relations with Ukraine, Belarus and Lithuania After 1990 in the Context of the Situation of National Minorities [PDF]

open access: yes, 2013
When we compare the contemporary ethnic structure and national policy of Poland and its eastern neighbours, we can see clear asymmetry in both quantitative and legal-institutional aspects.
Barwiński, Marek
core   +2 more sources

Elite‐Mass Linkages in the Preference Formation on Differentiated Integration [PDF]

open access: hybrid, 2022
Stefan Telle   +3 more
openalex   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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