Results 91 to 100 of about 604,284 (310)

The Human Capital-Intensive Firm and Coordination: Redefined Integration and Disintegration [PDF]

open access: yes
The aim of this paper is to reconsider the link between integration and disintegration. We argue that the conception of this link depends on the way one defines the firm and its coordinating role. We focus on studying the human capital-intensive firm. We
Cécile Cézanne, Olivier Sautel
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Differentiated integration contingent on objective ability: a federalist critique

open access: yesPerspectives on Federalism, 2018
This article is inspired by the 2017 discussions on the future of Europe (in particular some of the ideas debated in the White Paper on the Future of Europe, published by the European Commission) and the events that took place in the crises and post ...
Bardutzky Samo
doaj   +1 more source

Market Integration and Industrial Structure: Home Market Effects Revisited [PDF]

open access: yes
Does market size matter for industrial structure? This paper generalises the theory on home market effects to reconcile the recent debate by allowing for an endogenous expenditure share on differentiated goods.
Zhihao Yu
core  

A Multi-level Approach to Differentiated Integration: Distributive Policy, National Heterogeneity and Actors in the European Research Area [PDF]

open access: yes, 2015
This paper argues that differentiated integration can be understood more thoroughly by using a multi-level approach that conceives of the nation state as an aggregate of partly autonomous subunits and actors.
Fumasoli, Tatiana   +2 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Vertical integration and the licensing of innovation with a fixed fee or a royalty [PDF]

open access: yes
In this paper, we analyse a situation where a patent holder is considered as an upstream firm that can license its innovation to some downstream companies that compete on a final market with differentiated products. Licensing contract may be based either
Lemarié, S.
core  

Clubs within clubs: The Council of the Baltic Sea States (CBSS) and the Benelux as Macro-regions within the EU [PDF]

open access: yes, 2011
This paper deals with two examples of macro-regions in the EU: the Benelux and the Council of the Baltic Sea States (CBSS). Building on the distinction between “old” and “new” regionalism, it discusses some characteristics of regions in general, and of ...
Groenendijk, Nico
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Differentiated Integration in Europe After Brexit: A Legal Analysis

open access: yesEuropean Papers, 2019
(Series Information) European Papers - A Journal on Law and Integration, 2019 4(2), 447-469 | Article | (Table of Contents) I. Introduction. - II. Two visions of Europe. - II.1. A first cut at the argument. - II.2. An ever closer union. - II.3.
Giacinto della Cananea
doaj   +1 more source

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