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Thyroid Hormones in Differentiated Thyroid Cancer

Clinical Nuclear Medicine, 1994
In a study of 136 differentiated thyroid cancer patients referred for radioiodine therapy since January 1991, it was observed that 80 patients had metastatic disease. Of them, 51 had elevated levels of thyroglobulin (Tg), and of these 51 there were 15 patients who had functioning metastases with evidence of thyroid hormone synthesis by these metastases.
A M, Samuel, M N, Mehta, K B, Desai
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Poorly differentiated thyroid cancer

Current Opinion in Otolaryngology & Head and Neck Surgery, 2014
Poorly differentiated thyroid carcinomas (PDTCs) comprise a small subset of heterogeneous thyroid tumors, occupying an intermediate area between well differentiated follicular or papillary carcinoma and anaplastic carcinomas, from both a histopathogenetic and a clinical point of view.
Kepal N, Patel, Ashok R, Shaha
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Differentiated thyroid cancer: an update

Current Opinion in Oncology, 2011
The incidence of differentiated thyroid cancer (DTC) is increasing. There remains controversy regarding several aspects of its management, including the need for prophylactic central compartment neck dissection and use of recombinant human thyroid stimulating hormone (rhTSH) for ¹³¹I radioactive iodine remnant ablation in patients with low-risk disease.
Tracy S, Wang   +2 more
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Differentiated thyroid cancer in children

Head & Neck Surgery, 1985
AbstractDifferentiated thyroid cancer in children remains a controversial disease entity. Its incidence has markedly declined over the last decade since the use of radiotherapy in the treatment of benign conditions of the head, neck, and thorax was abandoned. Other etiologic factors have become relatively more important.
L F, De Keyser, A J, Van Herle
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Fatal differentiated thyroid cancer

Journal of Surgical Oncology, 1996
Thirty-five patients who died of differentiated thyroid cancer were analyzed for factors affecting survival. The neck was the most common initial site of recurrence (62.0%). The lung was the most common metastatic site (56.7%). Major sites associated with death were locoregional recurrence (neck and mediastinum: 48.6%) and bone metastases (22.9%).
T, Kobayashi   +4 more
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Aggressive differentiated thyroid cancer

European Journal of Surgical Oncology, 2018
Differentiated thyroid cancer is characteristically associated with an innocuous clinical course, but a minority of cases may manifest surprisingly aggressive behaviour. Such aggressive DTC are directly responsible for the majority of thyroid cancer related deaths.
Noor, Janjua, Volkert B, Wreesmann
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Thyroglobulin in differentiated thyroid cancer

Clinica Chimica Acta, 2015
Identification of differentiated thyroid cancer (DTC) is becoming increasingly common. Patients usually have an excellent prognosis. Most undergo total thyroidectomy, radioiodine ablation and treatment with suppressive doses of levothyroxine. Patients require long term follow-up which includes measurement of serum thyroglobulin (Tg).
Carol, Evans   +2 more
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Thyroid cancer: differentiated carcinoma

Cancer Treatment Reviews, 1996
disease. The anaplastic cancers present a totally different clinical picture as they grow and metastasize with explosive rapidity. Typically, they are inoperable at presentation and have no ability to concentrate iodine. Their prognosis is appalling, with external-beam radiotherapy providing only palliative treatment. Medullary carcinoma of the thyroid
C L, Harmer, V R, McCready
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Recurrent Differentiated Thyroid Cancer

Endocrine Practice, 2012
To discuss the risk of recurrence in patients with differentiated thyroid cancer and emphasize the importance of risk-group stratification.Common risk factors associated with recurrent thyroid cancer are outlined, and appropriate management strategies are reviewed.The overall prognosis in patients with differentiated thyroid cancer is excellent ...
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Thyroid hormone therapy in differentiated thyroid cancer

Endocrine, 2019
Surgery-with or without postoperative radioiodine-is the standard of care for most patients with differentiated thyroid carcinoma (DTC). Thyroid hormone replacement therapy is the mainstay of long-term medical management. Patients treated with total thyroidectomy and some who undergo lobectomy alone require thyroid hormone therapy to restore ...
Grani G.   +4 more
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