Case Report: Diagnostic challenges in differentiated-type vulvar intraepithelial neoplasia [PDF]
Differentiated-type vulvar intraepithelial neoplasia (dVIN) is typically HPV-independent and is most strongly linked to HPV-independent keratinizing squamous cell carcinoma (often well- to moderately differentiated).
Yuling Dong
exaly +7 more sources
Differentiated vulvar intraepithelial neoplasia long-term follow up and prognostic factors: An analysis of a large historical cohort [PDF]
Introduction Differentiated vulvar intraepithelial neoplasia (dVIN) is a high‐risk preinvasive vulvar lesion and precursor of human papillomavirus‐independent vulvar squamous cell carcinoma (VSCC).
Luca Bertero +2 more
exaly +5 more sources
Evaluation of Immunohistochemical Markers, CK17 and SOX2, as Adjuncts to p53 for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia (dVIN) [PDF]
Histological diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor of human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC), can be challenging, as features of dVIN may mimic those of non-dysplastic ...
Shatavisha Dasgupta +9 more
doaj +6 more sources
Correlation of histopathologic findings with clinical predictors of disease recurrence and progression to vulvar carcinoma in patients with differentiated vulvar intraepithelial neoplasia (dVIN) [PDF]
Objective: To evaluate predictors of recurrence and the risk of progression to carcinoma in patients with dVIN. Methods: 36 self-identified White patients with dVIN from 2011 to 2022 were identified.
Jill N.T. Roberts +3 more
doaj +4 more sources
The Vulvar Cancer Risk in Differentiated Vulvar Intraepithelial Neoplasia: A Systematic Review [PDF]
Differentiated vulvar intraepithelial neoplasia (dVIN) is the precursor of human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC). Given the rare incidence of dVIN, limited information on the exact cancer risk is available. We systematically reviewed the primary and recurrent VSCC risk in patients with dVIN, as well as the time to
Nikki Thuijs, Erica Wilthagen
exaly +5 more sources
Development of a risk assessment model for the recurrence of high-grade squamous intraepithelial lesions and differentiated vulvar intraepithelial neoplasia in Chinese cohort [PDF]
Objective To construct a sophisticated risk prediction model for the recurrence of high-grade squamous intraepithelial lesions (HSIL) and differentiated vulvar intraepithelial neoplasia (dVIN) after treatment. This model will help the early detection and
Xi Ye +6 more
doaj +4 more sources
Differentiated vulvar intraepithelial neoplasia (dVIN): the most helpful histological features and the utility of cytokeratins 13 and 17 [PDF]
Differentiated vulvar intraepithelial neoplasia (dVIN) is the precursor lesion of HPV-negative vulvar squamous cell carcinoma (VSCC). The histopathological diagnosis of dVIN can be challenging, as it often resembles vulvar non-neoplastic epithelial disorders (NNED), especially lichen sclerosus (LS).
Patricia C Ewing-Graham +1 more
exaly +6 more sources
The Varying Faces of Vulvar Neoplasia [PDF]
Vulvar neoplasia is on the rise and patients often present to dermatologists with lesions of varying morphology associated with pruritus, burning sensation, or pain.
Kavitha Athota +2 more
doaj +2 more sources
HPV-independent vulvar squamous cell carcinoma: a case report and review of the literature [PDF]
Vulvar cancer, a rare gynecological malignancy, accounts for 3-5% of cases and is most commonly squamous cell carcinoma. Prognosis is poorer in cancers unrelated to human papillomavirus (HPV), often associated with chronic inflammation.
Raphael Federicci Haddad +6 more
doaj +2 more sources
No viral association found in a set of differentiated vulvar intraepithelial neoplasia cases by human papillomavirus and pan-viral microarray testing. [PDF]
Vulvar Intraepithelial Neoplasia (VIN) is the precursor lesion of Vulvar Squamous Cell Carcinoma (VSCC), and the differentiated type (dVIN) is more frequently observed in relation to VSCC.
Ozlen Saglam +5 more
doaj +2 more sources

