Results 21 to 30 of about 1,742 (133)

Differentiated Vulvar Intraepithelial Neoplasia: A Brief Review of Clinicopathologic Features [PDF]

Archives of Pathology & Laboratory Medicine, 2018
Differentiated-type vulvar intraepithelial neoplasia (dVIN) is a non–human papilloma virus (HPV)-related precursor lesion to vulvar squamous carcinoma. The terminology has only become recognized clinically and histopathologically in recent years despite being described more than 50 years ago. As opposed to the HPV-related VIN (uVIN), dVIN has different
Cao, Jin, Sharon, Liang
openaire   +2 more sources

Vulval premalignant lesions: a review article [PDF]

Obstetrics & Gynecology Science
Vulvar intraepithelial neoplasia (VIN) is a noninvasive squamous lesion that is a precursor of vulvar squamous cell cancer. Currently, no screening tests are available for detecting VIN, and a biopsy is performed to confirm the clinical diagnosis ...
Sumedha Gupta, Sana Ahuja, Dheer Singh Kalwaniya, Saritha Shamsunder, Shalu Solanki   +4 more
doaj   +1 more source

Use of p53 immunohistochemistry can improve diagnostic agreement for differentiated vulvar intraepithelial neoplasia (dVIN): an international reproducibility study. [PDF]

Histopathology
Aims Differentiated or HPV‐independent vulvar intraepithelial neoplasia (dVIN) can progress rapidly to invasive cancer and accurate pathological diagnosis is essential to facilitate appropriate interventions. Histological similarities of dVIN with non‐neoplastic lesions, however, often make the diagnosis less ...
Dasgupta S, Van Rompuy AS, Bergeron C, Heller DS, Rush D, Plantier F, Scurry J, Roberts J, Bart J, Lambein K, Veprauskas K, Van de Vijver KK, Makkus LA, Kooreman L, Bleeker M, Mohamed MB, Selim MA, Alvarez MCR, Van Bockstal MR, Jean-Christophe N, Guzman P, Srinivasan R, Arora R, Ball R, Wilhelmus S, Koljenović S, van Kemenade FJ, Ewing-Graham PC.   +27 more
europepmc   +9 more sources

MALDI Mass Spectrometry Imaging Reveals Decreased CK5 Levels in Vulvar Squamous Cell Carcinomas Compared to the Precursor Lesion Differentiated Vulvar Intraepithelial Neoplasia [PDF]

International Journal of Molecular Sciences, 2016
Peter Hoffmann, Noor A Lokman, Martin K Oehler   +2 more
exaly   +2 more sources

Interobserver variability and the effect of education in the histopathological diagnosis of differentiated vulvar intraepithelial neoplasia [PDF]

Modern Pathology, 2013
No published data concerning intraobserver and interobserver variability in the histopathological diagnosis of differentiated vulvar intraepithelial neoplasia (DVIN) are available, although it is widely accepted to be a subtle and difficult histopathological diagnosis.
Einden, L.C.G. van den, Hullu, J.A. de, Massuger, L.F.A.G., Grefte, J.M.M., Bult, P., Wiersma, A., Engen-van Grunsven, A.C.H. van, Sturm, B., Bosch, S.L., Hollema, H., Bulten, J.   +10 more
openaire   +4 more sources

Differentiated Vulvar Intraepithelial Neoplasia Associated with Intraepithelial Neoplastic Spread [PDF]

Biomedical Journal of Scientific & Technical Research, 2019
Differentiated vulvar intraepithelial neoplasia (dVIN) associated with intraepithelial neoplastic spread and with usual vulvar intraepithelial neoplasia (uVIN) has not been studied...
openaire   +1 more source

Neoplasia intraepitelial vulvar: um problema atual Vulvar intraepithelial neoplasia: a current problem

Revista Brasileira de Ginecologia e Obstetrícia, 2008
A neoplasia intraepitelial da vulva (VIN) é uma denominação que foi introduzida incialmente pela International Society for Study of Vulvo-vaginal Diseases (ISSVD) e reconhecida posteriormente pela International Society of Gynaecological Pathology (ISGYP)
José Alberto Fonseca-Moutinho
doaj   +1 more source

Differential expression patterns of GATA3 in usual and differentiated types of vulvar intraepithelial neoplasia: potential diagnostic implications [PDF]

Modern Pathology, 2018
The two main precursors of vulvar squamous cell carcinoma, usual and differentiated vulvar intraepithelial neoplasia (VIN), have distinctive etiology, pathogenesis, and natural history. Usual type VIN is often associated with high-risk HPV and differentiated VIN has de novo p53 genetic alterations that are unrelated to HPV infection.
Abha, Goyal, Gloria, Zhang, Bin, Yang
openaire   +2 more sources

Two Distinct Pathways to Development of Squamous Cell Carcinoma of the Vulva

Journal of Skin Cancer, 2011
Squamous cell carcinoma (SCC) accounts for approximately 95% of the malignant tumors of the vaginal vulva and is mostly found in elderly women. The future numbers of patients with vulvar SCC is expected to rise, mainly because of the proportional ...
Yutaka Ueda, Takayuki Enomoto, Toshihiro Kimura, Kiyoshi Yoshino, Masami Fujita, Tadashi Kimura   +5 more
doaj   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source