Clinical characteristics, treatment patterns, and prognosis in vulvar cancer and vaginal cancer: a national multicenter retrospective study in China. [PDF]
Zhao X +16 more
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Depth of Invasion of 13 mm or Greater Accurately Predicted the Risk of Having a Node Positivity in Lymphadenectomy for Squamous Vulvar Cancer. [PDF]
Albuquerque RC +5 more
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Real-world outcomes of photodynamic therapy for HPV-associated lower genital tract lesions: a 2024-2025 gynecology follow-up cohort study. [PDF]
Wang L, Wang Y, Xu Z, Jiao X.
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Vulvar lichen sclerosus-lichen planus overlap: A case series with diagnostic and management implications. [PDF]
Chapman M, Etcheverry MJ, Kraus CN.
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Herein, the authors evaluate the diagnostic utility and limitations of GATA3 immunohistochemistry for the distinction of differentiated vulvar intraepithelial neoplasia (dVIN) from its potential mimics. Immunohistochemical studies for GATA3, p53, and p16 were performed on 124 pathologic vulvar tissues, inclusive of dVIN (n = 21), vulvar aberrant ...
Oluwole Fadare
exaly +3 more sources
Differentiated vulvar intraepithelial neoplasia contains Tp53 mutations and is genetically linked to vulvar squamous cell carcinoma [PDF]
Differentiated vulvar intraepithelial neoplasia is a unique precursor to vulvar squamous cell carcinoma that is typically HPV-negative and frequently associated with nuclear p53 staining. These features imply a mode of pathogenesis involving somatic mutations.
Christopher P Crum +2 more
exaly +3 more sources
ORF1p Is a Potential Novel Diagnostic Marker for Differentiated Vulvar Intraepithelial Neoplasia
International Journal of Gynecological Pathology, 2022Accurate diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN) can be challenging as histomorphologic features may be subtle and overlap with nondysplastic lesions. In practice, aberrant p53 expression supports the diagnosis, but a substantial percentage retains wild-type p53.
Gerda, Hofstetter +3 more
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Specific intraepithelial localization of mast cells in differentiated vulvar intraepithelial neoplasia and its possible contribution to vulvar squamous cell carcinoma development [PDF]
van de Nieuwenhof H P, Hebeda K M, Bulten J, Otte‐Holler I, Massuger L F A G, de Hullu J A & van Kempen L C L T (2010) Histopathology 57, 351–362 Specific intraepithelial localization of mast cells in differentiated vulvar intraepithelial neoplasia and its possible contribution to vulvar squamous cell carcinoma developmentAims: The aetiology of ...
Leon F A G Massuger +2 more
exaly +3 more sources

