Results 101 to 110 of about 2,784,026 (307)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Xbra modulates the activity of linker region phosphorylated Smad1 during Xenopus development
Scientific ReportsThe Bmp/Smad1 pathway plays a crucial role in developmental processes and tissue homeostasis. Mitogen-activated protein kinase (Mapk)/Erk mediated phosphorylation of Smad1 in the linker region leads to Smad1 degradation, cytoplasmic retention and ...
Santosh Kumar +6 more
doaj +1 more source
, 2018 Discussion du panel 1 du workshop "Does the future of the European Union depend on differentiation ?
Does the future of the European Union depend on differentiation ? Sources and effects of the logic of differentiation +1 more
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Stem Cell Reports, 2015 To develop a culture system for large-scale production of mature hepatocytes, liver progenitor cells (LPCs) with a high proliferation potential would be advantageous.
Taketomo Kido +7 more
doaj +1 more source
Introduction to Differentiation - How large should a University be?
, 2010 Making rational decisions often means thinking about small changes, and many of them revolve around the idea of the margin - the marginal change. A useful way of analysing marginal changes is by differentiation. (Duration 7 minutes 21 seconds). Part of a
METAL (Mathematics for Economics: enhancing Teaching and Learning)
core
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
auto-differentiation/XAD: v1.4.0
<p>This release fixes an issue with complex XAD types, updates documentation, and improves compiler support.</p> <p>Further details are listed below.</p> <h3>Added</h3> <ul> <li>Supporting Clang version 16 ...
hlahlou-dev +3 more
core +1 more source
STEM CELL GROWTH AND DIFFERENTIATION IN HYDRA ATTENUATA [PDF]
, 1979 The differentiation of nerve cells and nematocytes from interstitial stem cells in Hydra has been investigated under conditions of changing stem cell density.
Sproull, Frederick, David, Charles N.
core
Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation [PDF]
, 2009 We show that Indian Hedgehog (Ihh) regulates T-cell development and homeostasis in both fetal and adult thymus, controlling thymocyte number. Fetal Ihh-/- thymi had reduced differentiation to double-positive (DP) cell and reduced cell numbers compared ...
Outram, Susan V +17 more
core +1 more source