Results 181 to 190 of about 4,668,187 (354)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
EpCAM supports exit from pluripotency of embryonic stem cells via Eomes. [PDF]
Gong N +10 more
europepmc +1 more source
Biomimetic self-assembled nano-composite hydrogel promotes myoblast differentiation
Patel Akhil +5 more
openalex +1 more source
Differentiable functions of quaternion variables [PDF]
S. V. Lüdkovsky, F. Van Oystaeyen
openalex +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Emerging roles of microRNAs and other non-coding transcriptome in muscular dystrophies. [PDF]
Abdelrehim FG +5 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Expanding clones, expanding aneurysms through macrophage-to-osteoclast differentiation. [PDF]
Regan JA, Shah SH.
europepmc +1 more source

