Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Iron-Dependent JMJD1A-Mediated Demethylation of H3K9me2 Regulates Gene Expression During Adipogenesis in a Spatial Genome Organization-Dependent Manner. [PDF]
Masuda S+7 more
europepmc +1 more source
LncRNA NEAT1 sponges miR-214-3p to promote osteoblast differentiation through regulating the PI3K/AKT/mTOR pathway in aortic valve calcification. [PDF]
Xu R, Sun Y, Tian F, Zhao M.
europepmc +1 more source
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway. [PDF]
Chuang SC+5 more
europepmc +1 more source
Multi‐institutional study on image quality for a novel CBCT solution on O‐ring linac
Abstract Introduction This work presents a multi‐institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.
Luis Agulles‐Pedrós+11 more
wiley +1 more source
How leader-member exchange affects university teachers' scholarship of teaching and learning performance: a comprehensive analysis of psychological capital, LMX differentiation, and traditionality. [PDF]
Fang J, Zhang Q, Rao P, Ouyang G.
europepmc +1 more source
Abstract Purpose This study aims to evaluate the accuracy of the frameless linear accelerator‐based stereotactic radiosurgery (FSRS) system incorporating cone‐beam CT (CBCT), six degrees of freedom (6‐DoF) couch, room laser, and surface image‐guided (SG) systems.
Hao‐Wen Cheng+4 more
wiley +1 more source
Biodentine Stimulates Calcium-Dependent Osteogenic Differentiation of Mesenchymal Stromal Cells from Periapical Lesions. [PDF]
Eraković M+9 more
europepmc +1 more source
Abstract Purpose Breast cancer is a neoplastic disease with high prevalence among women. Radiotherapy is one of the principal treatment modalities for this disease, but it poses significant challenges. This study aimed to compare and evaluate the technical and dosimetric performance of conventional C‐arm linac systems and a new design, Halcyon, in the ...
Mustafa Çağlar+8 more
wiley +1 more source
Advances and challenges in identifying precursors of memory CD4<sup>+</sup> T cells. [PDF]
Liu J, Song W, Tang H.
europepmc +1 more source