Results 201 to 210 of about 6,101,774 (389)

Differential inequalities and differential games

open access: yesJournal of Mathematical Analysis and Applications, 1973
A.N.V Rao, V Lakshmikantham
openaire   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

VSX1 EXPRESSION INITIALLY DESCRIBED IN THE V2 SPINAL INTERNEURON PRECURSOR CELLS IS ALSO PRESENT IN THE ADULT SPINAL CORD AND MAINTAINED AFTER A TRAUMATIC INJURY

open access: yesIBRO Neuroscience Reports, 2023
Ana Dominguez-Bajo   +4 more
doaj  

Transcriptome analysis reveals the sex-switching mechanism of juvenile hermaphroditism in silver pomfret (Pampus argenteus). [PDF]

open access: yesBiol Sex Differ
Li Y   +13 more
europepmc   +1 more source

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