Results 61 to 70 of about 6,101,774 (389)
Biomolecules, 2020 The Wnt Inhibitory Factor 1 (Wif1), known to inhibit Wnt signaling pathways, is composed of a WIF domain and five EGF-like domains (EGF-LDs) involved in protein interactions.
Florian Pennarubia +6 more
doaj +1 more source
Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds. [PDF]
, 2019 The instructive capabilities of extracellular matrix-inspired materials for osteoprogenitor differentiation have sparked interest in understanding modulation of other cell types within the bone regenerative microenvironment.
Bischoff, David +11 more
core
Cannabidiol stimulates AML-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner [PDF]
, 2015 Glioma stem-like cells (GSCs) correspond to a tumor cell subpopulation, involved in glioblastoma multiforme (GBM) tumor ini- tiation and acquired chemoresistance.
Amantini, Consuelo +7 more
core +2 more sources
Differentiating the differential rotation effect
Acta Psychologica, 2012 As an observer views a picture from different viewing angles, objects in the picture appear to maintain their orientation relative to the observer. For instance, the eyes of a portrait appear to follow the observer as he or she views the image from different angles. We have explored this rotation effect, often called the Mona Lisa effect.
Heiko Hecht, Evgenia Boyarskaya
openaire +3 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Nature Communications, 2017 Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembly ...
Ning Huang +7 more
doaj +1 more source
Stem Cell Reports, 2017 The lymphoid-myeloid transdifferentiation potentials of members of the C/EBP family (C/EBPα, β, δ, and ε) were compared in v-Abl-immortalized primary B cells. Conversion of B cells to macrophages was readily induced by the ectopic expression of any C/EBP,
Branko Cirovic +7 more
doaj +1 more source
HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. [PDF]
, 2019 Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation.
Chen, Yifang +8 more
core +1 more source
Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression [PDF]
, 2006 PURPOSE: The precise molecular cues required for photoreceptor development are still unknown. Pax6 and Crx are essential during early retinal development and for photoreceptor differentiation, respectively.
Garelli, Andres +2 more
core +2 more sources
Differentiable projections and differentiable semigroups [PDF]
Proceedings of the American Mathematical Society, 1973 Suppose X is a Banach space, G is a connected open subset of X, and p is a continuously Fr6chet differentiable function from G into G satisfying p(p(x))=p(x) for each x in G. We prove that p(G) is a differentiable submanifold of X and use this result to show that the maximal subgroup containing an idempotent in a differentiable semigroup is a Lie group.
openaire +2 more sources