Graphics calculators in the mathematics curriculum: Integration or differentiation? [PDF]
, 1996 Graphics calculators are examples of powerful technologies that we want our students to learn to use well. However if we use them in our courses only for learning, students will not regard them with due importance because they are not integrated into the
Kissane, B., Bradley, J., Kemp, M.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Dynamic Effect of Young’s Modulus on Attachment and Differentiation of Mouse Embryonic Stem Cells [PDF]
, 2015 Embryonic stem cells have generated much interest due to their ability to differentiate into any cell type within the body. This ability could potentially allow for scientists and engineers to develop a number of therapies for diseases, which currently ...
Ali, S
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Organisational Structures in Network Industries – An Application to the Railway Industry [PDF]
This paper analyses the incentives to upgrade input quality in vertically related (network) industries. Upstream investments have a biased effect on the downstream companies and lead to vertical product differentiation. Different vertical structures such
Benjamin Pakula, Georg Götz
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Images of Europeans: In-Group Trust and Support for European Integration [PDF]
, 2009 Prior research on citizen support for European integration does not consider how individuals’ evaluations of European nationalities are associated with support.
Genna, Gaspare M.
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Implications of wage bargaining systems on regional differentiation in the European Union [PDF]
The theoretical literature has argued that a centralized wage bargaining system may result in low regional wage differentiation and high regional unemployment differentials.
Luminita VOCHITA +2 more
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Differentiation and integration by using matrix inversion
Journal of Applied Mathematics and Computational Mechanics, 2014 Dagmara Matlak +3 more
doaj +1 more source