Results 81 to 90 of about 1,306,756 (298)
On the adjoint of a symmetric operator [PDF]
In general it is a non-trivial task to determine the adjoint S* of an unbounded symmetric operator S in a Hilbert or Krein space. We propose a method to specify S* explicitly which makes use of two boundary mappings that satisfy an abstract Green's ...
Meda S. +47 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
auto-differentiation/xad: v1.5.2
<h2>What's Changed</h2> <p>This is a patch release after factoring out the Python bindings, to get the versioning consistent with the xad-py repository.</p> <ul> <li>Updated naming of QuantLib-Risks by @auto ...
Auto Differentiation Dev Team +4 more
core +1 more source
Operator identities for standard weighted Bergman shift and Toeplitz operators [PDF]
We prove an operator identity for the shift operator in the scale of standard weighted Bergman spaces in the unit disc. This operator identity is then applied in the context of functional calculus for the shift operator and a characterization of harmonic
Olofsson, Anders +3 more
core +1 more source
The Fourier-based gradient field integration method can efficiently reconstruct transparent surfaces from the measured gradient data in the Shape-from-polarization method.
Zhuang Sun +5 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
auto-differentiation/XAD: v1.5.0
<h2>Added</h2> <ul> <li>Python bindings as <a href="https://pypi.org/project/xad-autodiff/">xad-autodiff</a> in https://github.com/auto-differentiation/XAD/pull/98</li> <li>Added <code>std::is_signed&
Auto Differentiation Dev Team +4 more
core +1 more source
STECHKIN PROBLEM FOR A DIFFERENTIATION OPERATOR WITH ASYMMETRIC CONSTRAINTS
The Landau–Kolmogorov inequality estimates the norm of an intermediate derivative by the product of the norms of the function and its highest-order derivative.
Nikita S. Payuchenko
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

