Results 71 to 80 of about 1,501,299 (295)

Curvature perturbation spectrum from false vacuum inflation

, 2008
In the inflationary cosmology it occurs frequently that the inflaton field is trapped in a local, transient minimum with non-zero vacuum energy. The difficulty regarding the curvature perturbation produced during such a stage is that classically the ...
A.R. Liddle, G. Dvali, J. Choe, Jinn-Ouk Gong, Misao Sasaki, WMAP collaboration   +5 more
core   +1 more source

An Item Analysis of Written Multiple-Choice Questions: Kashan University of Medical Sciences [PDF]

, 2012
Background: Multiple Choice Questions (MCQs) are one of the most common types of exams used in evaluation of students in any educational setting. The question items making up these exams need to be examined if they are to meaningfully contribute to the ...
Assarian, M., Azarbad, Z., Bigdeli, M., Masoudi Alavi, N., Sayyah, M., Soleymani, A., Vakili, Z.   +6 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

The relationship between classical item characteristics and item response time on computer-based testing [PDF]

Korean Journal of Medical Education, 2019
Purpose This study investigated the relationship between the item response time (iRT) and classic item analysis indicators obtained from computer-based test (CBT) results and deduce students’ problem-solving behavior using the relationship.
Yoo-mi Chae, Seok Gun Park, Ilyong Park
doaj   +1 more source

Experimental evaluation of Kuhn's geometric index of reduction and the flat-flake problem [PDF]

, 2005
This paper presents the results of an experiment designed to explore the performance of Kuhn's Geometric Index of Unifacial Reduction [S. Kuhn, A geometric index of reduction for unifacial stone tools, Journal of Archaeological Science 17 (1990) 585-593]
Clarkson, Clarkson, Close, Davis, Dibble, Dibble, Dibble, Dibble, Dibble, Gordon, Hiscock, Hiscock, Hiscock, Hiscock, Hiscock, Holdaway, Kuhn, Neeley, Odell, Shott, Yvorra   +20 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Analyzing the quality of multiple-choice questions in microbiology for second-year MBBS students

MGM Journal of Medical Sciences
Background and Objective: According to the 2023 Graduate Medical Education Regulations by the National Medical Commission for competency-based medical education in the MBBS curriculum, 20% of assessment questions are now multiple-choice questions (MCQs ...
Gurjeet Singh, Raksha Singh, Nilakantan Ananthakrishnan   +2 more
doaj   +1 more source

Item statistics derived from three-option versions of multiple-choice questions are usually as robust as four- or five-option versions: implications for exam design. [PDF]

, 2018
Different versions of multiple-choice exams were administered to an undergraduate class in human physiology as part of normal testing in the classroom. The goal was to evaluate whether the number of options (possible answers) per question influenced the ...
Loudon, Catherine, Macias-Muñoz, Aide
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source