Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Cascadable all-optical NAND gates using diffractive networks
Owing to its potential advantages such as scalability, low latency and power efficiency, optical computing has seen rapid advances over the last decades.
Yi Luo, Deniz Mengu, Aydogan Ozcan
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Recent results on diffractive and forward physics at HERA
Recent studies on diffractive processes in ep scattering at HERA are reviewed. Heavy quark production in diffractive processes was studied by tagging a D* meson in diffractive DIS events.
Yuji Yamazaki
doaj +1 more source
Universal linear intensity transformations using spatially incoherent diffractive processors
Under spatially coherent light, a diffractive optical network composed of structured surfaces can be designed to perform any arbitrary complex-valued linear transformation between its input and output fields-of-view (FOVs) if the total number (N) of ...
Md Sadman Sakib Rahman +4 more
doaj +1 more source
Diffracting diffractive readings of texts as methodology: Some propositions
Re-turning to our experiences of putting a diffractive methodology to work ourselves, as well as engaging with the writings of Donna Haraway and Karen Barad, we produce some propositions regarding a diffractive methodology for researchers to consider ...
Bozalek, Vivienne, Murrisa, Karin
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
DIFFRACTIVE AND NON-DIFFRACTIVE BEAMS AND PULSES; A COMPARATIVE STUDY [PDF]
"Analytical methods are described which allow us to perform a comparative study of diffractive and non-diffractive beams and pulses. Our description first reviews basic properties of the Fresnel diffraction integral applied for calculating the ...
Etna Yáñez
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

