Results 1 to 10 of about 75,303 (197)
Diagnostic Problems in Diffuse Axonal Injury. [PDF]
Diagnostics (Basel), 2020 In this study, three problems associated with diagnosing diffuse axonal injury (DAI) in patients with traumatic brain injury are reviewed: the shortage of scientific evidence supporting the 6-hour loss of consciousness (LOC) diagnostic criterion to discriminate concussion and DAI, the low sensitivity of conventional brain MRI in the detection of DAI ...
Jang SH.
europepmc +8 more sources
Brainstem Diffuse Axonal Injury and Consciousness. [PDF]
J Clin Imaging Sci, 2019 Background: Severe traumatic brain injuries (TBI), commonly due to motor vehicle accidents may cause death and long-term disability especially when the acceleration-deceleration force on the brain is massive. This may cause shearing of the axonal connections within the cerebral cortex and brainstem in a process referred to as diffuse axonal injury ...
Sandhu S +6 more
europepmc +6 more sources
Diffuse Axonal Injury in the Rat Brain: Axonal Injury and Oligodendrocyte Activity Following Rotational Injury. [PDF]
Brain Sci, 2020 Traumatic brain injury (TBI) commonly results in primary diffuse axonal injury (DAI) and associated secondary injuries that evolve through a cascade of pathological mechanisms. We aim at assessing how myelin and oligodendrocytes react to head angular-acceleration-induced TBI in a previously described model. This model induces axonal injuries visible by
Losurdo M, Davidsson J, Sköld MK.
europepmc +9 more sources
Myelin Damage in Diffuse Axonal Injury. [PDF]
Front Neurosci, 2019 Diffuse axonal injury (DAI) is characterized by delayed axonal disconnection. Although the effect of DAI on axonal pathology has been well documented, there is limited information regarding the role of myelin in the pathogenesis of DAI. We used a modified Marmarou method to create a moderate DAI model in adult rat and examined the corpus callosum and ...
Mu J +6 more
europepmc +6 more sources
Early computed tomography for acute post-traumatic diffuse axonal injury: a systematic review. [PDF]
Neuroradiology, 2020 Purpose Diffuse axonal injury (DAI) is the rupture of multiple axons due to acceleration and deceleration forces during a closed head injury. Most traumatic brain injuries (TBI) have some degree of DAI, especially severe TBI.
Figueira Rodrigues Vieira G +1 more
europepmc +4 more sources
Prognosis of diffuse axonal injury with traumatic brain injury. [PDF]
J Trauma Acute Care Surg, 2018 BACKGROUND Determine the prognostic impact of magnetic resonance imaging (MRI)-defined diffuse axonal injury (DAI) after traumatic brain injury (TBI) on functional outcomes, quality of life, and 3-year mortality. METHODS This retrospective single center cohort included adult trauma ...
Humble SS +11 more
europepmc +6 more sources
Diffuse axonal injury predicts neurodegeneration after moderate-severe traumatic brain injury. [PDF]
Brain : a journal of neurology, 2020 Traumatic brain injury is associated with elevated rates of neurodegenerative diseases such as Alzheimer's disease and chronic traumatic encephalopathy. In experimental models, diffuse axonal injury triggers post-traumatic neurodegeneration, with axonal ...
Neil S N Graham +7 more
semanticscholar +6 more sources
Longitudinal assessment of magnetization transfer ratio, brain volume, and cognitive functions in diffuse axonal injury. [PDF]
Brain Behav, 2022 Diffuse axonal injury (DAI) is a frequent mechanism of traumatic brain injury (TBI) that triggers a sequence of parenchymal changes that progresses from focal axonal shear injuries up to inflammatory response and delayed axonal disconnection.
Macruz FBC +9 more
europepmc +2 more sources
Contemporary insight into diffuse axonal injury [PDF]
Folia Medica, 2021 Diffuse axonal injury (DAI) is present in approximately 50% of the cases with severe traumatic brain injury. It is one of the leading causes of morbidity and mortality among children and young individuals worldwide. Generally, DAI occurs as a result of high-velocity accidents.
Borislav Kitov +3 more
openaire +5 more sources
Outcome of diffuse axonal injury in moderate and severe traumatic brain injury. [PDF]
Surg Neurol Int, 2021 Background: Diffuse axonal injury (DAI) is a common presentation in neurotrauma. Prognosis is variable but can be dependent on the initial presentation of the patient. In our study, we evaluated the outcome of diffuse axonal injury.
Javeed F, Rehman L, Afzal A, Abbas A.
europepmc +2 more sources