Results 21 to 30 of about 22,064 (234)

The pathobiology of moderate diffuse traumatic brain injury as identified using a new experimental model of injury in rats

open access: yesNeurobiology of Disease, 2004
Experimental models of traumatic brain injury have been developed to replicate selected aspects of human head injury, such as contusion, concussion, and/or diffuse axonal injury.
Ibolja Cernak   +7 more
doaj   +1 more source

Diffuse Axonal Injury After Traumatic Brain Injury

open access: yesPediatric Neurology Briefs, 2004
Forty children and adolescents with traumatic brain injury and suspected diffuse axonal injury were studied for hemorrhagic lesions, using a high-resolution magnetic resonance imaging susceptibility-weighted technique, at Loma Linda University Medical ...
J Gordon Millichap
doaj   +1 more source

Forensic and clinical diagnosis in "shaken baby syndrome", between child abuse and iatrogenic abuse

open access: yesJournal of Mind and Medical Sciences, 2017
“Shaken baby syndrome” in child abuse cases is a challenge for pediatrician and forensic experts, often a diagnosis of exclusion, with overwhelming moral and legal implications.
Roxana M. Duncea   +3 more
doaj   +1 more source

Diffuse Axonal Injury in the Rat Brain: Axonal Injury and Oligodendrocyte Activity Following Rotational Injury

open access: yesBrain Sciences, 2020
Traumatic brain injury (TBI) commonly results in primary diffuse axonal injury (DAI) and associated secondary injuries that evolve through a cascade of pathological mechanisms.
Michela Losurdo   +2 more
doaj   +1 more source

Immediate induction of varicosities by transverse compression but not uniaxial stretch in axon mechanosensation

open access: yesActa Neuropathologica Communications, 2022
Uniaxial stretch is believed to drive diffuse axonal injury (DAI) in mild traumatic brain injury (mTBI). Axonal varicosities are enlarged structures along axonal shafts and represent a hallmark feature of DAI.
Chao Sun   +4 more
doaj   +1 more source

Influence of liposome-mediated APOE3 gene transfection of brain tissue on diffuse axonal injury, caused by traumatic brain injury, in experiment

open access: yesUkrainian Neurosurgical Journal, 2011
The goal of study was to estimate the structural damage of axons in rats with severe traumatic brain injury (TBI), and the possibilities of such disorders correction by means of gene therapy that launches the synthesis of e3 isoform of ...
Vadym Biloshytsky   +2 more
doaj   +1 more source

Current Opportunities for Clinical Monitoring of Axonal Pathology in Traumatic Brain Injury

open access: yesFrontiers in Neurology, 2017
Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces transmitted to the brain during impact.
Parmenion P. Tsitsopoulos   +4 more
doaj   +1 more source

Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury

open access: yesJournal of Neuroinflammation, 2010
Background Diffuse axonal injury in patients with traumatic brain injury (TBI) can be associated with morbidity ranging from cognitive difficulties to coma.
Chrzaszcz MaryAnn   +3 more
doaj   +1 more source

Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments

open access: yesFrontiers in Cellular Neuroscience, 2014
Traumatic brain injury from penetrating or closed forces to the cranium can result in a range of forms of neural damage, which culminate in mortality or impart mild to significant neurological disability.
Declan Guenter Siedler   +9 more
doaj   +1 more source

Current contribution of diffusion tensor imaging in the evaluation of diffuse axonal injury

open access: yesArquivos de Neuro-Psiquiatria
Traumatic brain injury (TBI) is the number one cause of death and morbidity among young adults. Moreover, survivors are frequently left with functional disabilities during the most productive years of their lives.
Daphine Centola Grassi   +3 more
doaj   +1 more source

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