Results 61 to 70 of about 432,565 (300)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
NIR diffuse reflectance spectral of RC-IJP.
, 2014 NIR diffuse reflectance spectral of RC-IJP.
Bo Jiang (76119), Yu Dong Huang (645890)
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Diffusion of Innovations: Some Reflections [PDF]
International Journal of the Economics of Business, 2018 This paper discusses a number of interrelated topics relating to the economics of innovation diffusion that merit further research and study. These topics encompass: how innovations are not just technological, may be horizontal or vertical, and may develop over time; the role in the diffusion process of complementarities across and substitutability ...
openaire +1 more source
Accurate and fast event-based shape measurement of mixed reflectance scenes
Nature CommunicationsEvent-based structured light systems have recently emerged as an exciting alternative to frame-based triangulation for 3D measurement of diffuse surfaces, offering high dynamic range and fast capture speed, but at the cost of reduced data quality ...
Aniket Dashpute +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Reflected Diffusion Processes with Jumps
The Annals of Probability, 1985 In this paper, the authors study the question of building solutions of stochastic differential equations with reflecting boundary conditions, corresponding to reflected diffusion processes with jumps. To do so, they adapt to the case of jump processes the penalty argument used by many authors.
Menaldi, Jose-Luis, Robin, Maurice
openaire +3 more sources
Materiais SiO2-TiO2 para a degradação fotocatalítica de diuron
Química Nova, 2011 SiO2-TiO2 materials prepared by sol-gel method were evaluated in the photocatalytic degradation of diuron. The materials were prepared with and without surfactant cetyltrimethylammonium chloride at different temperatures (25, 50 and 100 ºC).
Arthur Alaím Bernardes +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source