Results 101 to 110 of about 3,615,865 (367)

Capacity of Diffusion based Molecular Communication Networks over LTI-Poisson Channels [PDF]

arXiv, 2014
In this paper, the capacity of a diffusion based molecular communication network under the model of a Linear Time Invarient-Poisson (LTI-Poisson) channel is studied. Introduced in the context of molecular communication, the LTI-Poisson model is a natural extension of the conventional memoryless Poisson channel to include memory. Exploiting prior art on
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Mexican Hispanics show significant improvement in lung function approximately 1 year after having severe COVID‐19

Experimental Physiology
The long‐term effects of COVID‐19 on lung function are not understood, especially for periods extending beyond 1 year after infection. This observational, longitudinal study investigated lung function in Mexican Hispanics who experienced severe COVID‐19,
Arturo Cortes‐Telles, Luis Alberto Solís‐Díaz, Heidegger Mateos‐Toledo, Jordan A. Guenette, Gerald Stanley Zavorsky   +4 more
doaj   +1 more source

Capacities and Optimal Input Distributions for Particle-Intensity Channels [PDF]

arXiv, 2020
This work introduces the particle-intensity channel (PIC) as a model for molecular communication systems and characterizes the capacity limits as well as properties of the optimal (capacity-achieving) input distributions for such channels. In the PIC, the transmitter encodes information, in symbols of a given duration, based on the probability of ...
arxiv  

High-altitude exposure of three weeks duration increases lung diffusing capacity in humans.

Journal of applied physiology, 2011
BACKGROUND high-altitude adaptation leads to progressive increase in arterial Pa(O2). In addition to increased ventilation, better arterial oxygenation may reflect improvements in lung gas exchange.
P. Agostoni, E. Swenson, M. Bussotti, M. Revera, P. Meriggi, A. Faini, C. Lombardi, G. Bilo, A. Giuliano, D. Bonacina, P. Modesti, G. Mancia, G. Parati   +12 more
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Nutritional status and airflow obstruction: two independent contributors to CO diffusing capacity impairment in COPD

Monaldi Archives for Chest Disease, 2005
Background. The association between weight loss and Chronic Obstructive Pulmonary Disease (COPD) has been recognised from many years. Based on the evidence that nutritional status reflects metabolic disturbances in COPD, the relationship between body ...
S. Baldi, G.D. Pinna, P. Crotti, S. Montemartini, E. Dacosto, F. Fanfulla, C. Fracchia, C. Bruschi   +7 more
doaj   +1 more source

Application of carbon monoxide diffusing capacity in the mouse lung.

Journal of applied physiology, 2011
In the past decade the mouse has become the primary animal model of a variety of lung diseases. To assess various mechanisms underlying such pathologies, it is essential to make functional measurements that can reflect the developing pathology.
J. Fallica, Sandhya Das, M. Horton, W. Mitzner   +3 more
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source