Results 51 to 60 of about 3,778,907 (367)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Postural variation of pulmonary diffusing capacity as a marker of lung microangiopathy in Indian patients with type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2016
Introduction: Diabetes mellitus (DM) is characterized by the presence of chronic hyperglycemia and formation of advanced glycation end products (AGEs). Interaction between AGE and its receptor leads to endothelial damage and microangiopathy.
Avinash Kumar, Geetanjali Bade, Anjali Trivedi, Viveka P Jyotsna, Anjana Talwar   +4 more
doaj   +1 more source

The need for race-specific reference equations for pulmonary diffusing capacity for nitric oxide

BMC Pulmonary Medicine, 2021
Background Few reference equations exist for healthy adults of various races for pulmonary diffusing capacity for nitric oxide (DLNO). The purpose of this study was to collect pilot data to demonstrate that race-specific reference equations are needed ...
Gerald Stanley Zavorsky, Ahmad Saleh Almamary, Mobarak Khalid Alqahtani, Shi Huh Samuel Shan, Douglas Shawn Gardenhire   +4 more
doaj   +1 more source

Continuous and correlated nucleation during nonstandard island growth at Ag/Si(111)-7x7 heteroepitaxy

, 2004
We present a combined experimental and theoretical study of submonolayer heteroepitaxial growth of Ag on Si(111)-7x7 at temperatures from 420 K to 550 K when Ag atoms can easily diffuse on the surface and the reconstruction 7x7 remains stable.
B. Voigtländer, E. Vasco, I. Ošt’ádal, J. Mysliveček, J.-L. Li, J.A. Venables, K. Cho, K. Takayanagi, L. Vitali, M. Kotrla, O. Custance, P. Kocán, P. Sobotík, P. Sobotík, P. Sobotík, P. Sobotík, S. Clarke, S. Tosch, T. Jarolímek, Y. Tanishiro   +19 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Is Lymphopenia Detected in Sarcoidosis Associated with the Disease Activity?

Southern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]The association of lymphopenia detected in patients with sarcoidosis with disease activity was investigated in the present study.[¤]METHODS[|]Patients who were diagnosed as having sarcoidosis and healthy volunteers/individuals with no ...
Coşkun Doğan, Sevda Şener Cömert, Benan Çağlayan, Elif Torun Parmaksız, Nesrin Kıral, Recep Demirhan, Ali Fidan, Seda Beyhan Sağmen   +7 more
doaj   +1 more source

Absolute lung size and the sex difference in breathlessness in the general population. [PDF]

PLoS ONE, 2018
Breathlessness is associated with major adverse health outcomes and is twice as common in women as men in the general population. We evaluated whether this is related to their lower absolute lung volumes.Cross-sectional analysis of the population-based ...
Magnus Ekström, Josefin Sundh, Linus Schiöler, Eva Lindberg, Annika Rosengren, Göran Bergström, Oskar Angerås, Jan Hedner, John Brandberg, Björn Bake, Kjell Torén   +10 more
doaj   +1 more source

Relationship between diffusion capacity and small airway abnormality in COPDGene. [PDF]

, 2019
Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but the relationship between SAD and DLCO is undescribed. We hypothesized that in mild COPD,
Casaburi, Richard, Criner, Rachel N, Curtis, Jeffrey L, Galbán, Craig J, Han, Mei Lan K, Hatt, Charles R, Kazerooni, Ella A, Labaki, Wassim W, Lynch, David A, MacIntyre, Neil R, Make, Barry J, Martinez, Fernando J, McCormack, Meredith C   +12 more
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference [PDF]

, 2010
The response characteristics of the 6 minute walk test (6MWT) in studies of idiopathic pulmonary fibrosis (IPF) are only poorly understood, and the change in walk distance that constitutes the minimum important difference (MID) over time is ...
Behr, Jürgen, Brown, Kevin K., du Bois, Roland M., King, Talmadge E., Raghu, Ganesh, Swigris, Jeffrey J., Wamboldt, Frederick S.   +6 more
core   +1 more source