Results 61 to 70 of about 2,527,767 (256)
Interview guide used across 5 test facilities in 3 African countries to explore enablers, barriers and effects of a research capacity strengthening programme, targeting development of a Quality Management System compliant with Good Laboratory Practice ...
Capacity Research, Centre for
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Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Table 1: Location, institution type, focal science and number of participants interviewed in each capacity ...
Centre for Capacity Research
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The effect of tiotropium on the pulmonary diffusing capacity
To our knowledge, there is no data oil the effect of tiotropium on pulmonary gas exchange in healthy subjects. The aim of this study was to assess the effects of tiotropium on pulmonary diffusing capacity.
Gonlugur, U.
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A modeling approach to the estimation of CO diffusing capacity
Standard methods of measuring the diffusing capacity of the lung for CO are susceptible to inhomogeneity and to errors in the performance of a breathing maneuver by the subject.
G. K. Prisk, A. E. McKinnon
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Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Standards for pulmonary diffusing capacity
Karbonmonoksit difüzyon kapasitesine aynı zamanda transfer faktör de denilmektedir. Akciğerin difüzyon kapasitesinin ölçülmesinde en yaygın kullanılan teknik tek-nefes yöntemidir.
Tanseli E. Günlügür +1 more
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New insights into the aspects of pulmonary diffusing capacity in Fontan patients
BACKGROUND: Patients with a functionally univentricular heart, palliated a.m. Fontan, consequently have non-pulsatile pulmonary blood flow and are known to have a reduced pulmonary diffusing capacity. However, the cause of this reduction remains unclear.
Lars Søndergaard +13 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

