Results 41 to 50 of about 2,527,767 (256)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Interplay between the morphometry of the lungs and the mode of locomotion in birds and mammals
We studied the lung diffusion parameters of two species of birds and two species of mammals to explore how structural and functional features may be paralleled by differences in life style or phylogenetic origin.
DANIELA FIGUEROA +4 more
doaj
Background With the development and market launch of several new domestic lung diffusing capacity testing instruments, the clinical reliability of the MeHow MeAir 9000 spirometer, featuring a novel turning valve structure, needs to be validated ...
Shihua Yao +13 more
doaj +1 more source
Introduction: Diabetes mellitus (DM) is characterized by the presence of chronic hyperglycemia and formation of advanced glycation end products (AGEs). Interaction between AGE and its receptor leads to endothelial damage and microangiopathy.
Avinash Kumar +4 more
doaj +1 more source
Diffusing capacity predicts operative mortality but not long-term survival after resection for lung cancer [PDF]
Objectives: We sought to determine whether diffusing capacity influences operative mortality and long-term survival after resection for lung cancer. Methods: We retrospectively reviewed the case histories of patients who underwent major resection for ...
Olak, Jemi, Wang, Jun, Ferguson, Mark K.
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Is Lymphopenia Detected in Sarcoidosis Associated with the Disease Activity?
INTRODUCTION[|]The association of lymphopenia detected in patients with sarcoidosis with disease activity was investigated in the present study.[¤]METHODS[|]Patients who were diagnosed as having sarcoidosis and healthy volunteers/individuals with no ...
Coşkun Doğan +7 more
doaj +1 more source
Regional diffusing capacity in normal lungs during a slow exhalation
From an analysis of carbon monoxide uptake and xenon-133 distribution after two bolus inhalations of these gases, we calculated regional diffusing capacity in the upper and lower volume halves of the lungs during the middle 60% of an exhaled vital ...
N. R. MacIntyre, J. A. Nadel
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

