Results 61 to 70 of about 3,778,907 (367)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

COMPARING DIFFUSING CAPACITY REFERENCE EQUATION PERFORMANCE IN EVALUATING ABNORMAL DLCO IN POST-PNEUMONIA UGANDAN ADULTS [PDF]

, 2023
Katerina L. Byanova, JESSICA FITZPATRICK, Ingvar Sanyu, Josephine Zawedde, Patrick Byanyima, J.R. Branchini, Michelle Zhang, Rebecca Abelman, Abdulwahab Sessolo, Nirav R. Bhakta, J A Lin, Peter W. Hunt, William Worodria, LAURENCE HUANG   +13 more
openalex   +1 more source

The Reliability of a Novel Structured Testing Device for Single-breath Lung Carbon Monoxide Uptake: A Randomized Comparison Crossover Study

BMC Pulmonary Medicine
Background With the development and market launch of several new domestic lung diffusing capacity testing instruments, the clinical reliability of the MeHow MeAir 9000 spirometer, featuring a novel turning valve structure, needs to be validated ...
Shihua Yao, Tuping Fu, Kuiqing Lin, Zhongping Wu, Shubing Chen, Liping Zhong, Beilan Shen, Yanqing Xie, Jiaying An, Xudong Wang, Wenting Liu, Xinxin Yu, Jinping Zheng, Yi Gao   +13 more
doaj   +1 more source

Predictors of Diffusing Capacity in Children With Sickle Cell Disease: A Longitudinal Study

Frontiers in Pediatrics, 2021
Background: Gas exchange abnormalities in Sickle Cell Disease (SCD) may represent cardiopulmonary deterioration. Identifying predictors of these abnormalities in children with SCD (C-SCD) may help us understand disease progression and develop informed ...
Pritish Mondal, Vishal Midya, Arshjot Khokhar, Shyama Sathianathan, Erick Forno   +4 more
doaj   +1 more source

The second will be first: competition on directed networks [PDF]

, 2015
Multiple sinks competition is investigated for a walker diffusing on directed complex networks. The asymmetry of the imposed spatial support makes the system non transitive.
Bagnoli, Franco, Cencetti, Giulia, Di Patti, Francesca, Fanelli, Duccio   +3 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Interplay between the morphometry of the lungs and the mode of locomotion in birds and mammals

Biological Research, 2007
We studied the lung diffusion parameters of two species of birds and two species of mammals to explore how structural and functional features may be paralleled by differences in life style or phylogenetic origin.
DANIELA FIGUEROA, RICARDO OLIVARES, MICHEL SALABERRY, PABLO SABAT, MAURICIO CANALS   +4 more
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The Single-Breath Diffusing Capacity of CO and NO in Healthy Children of European Descent

PLoS ONE, 2014
Rationale The diffusing capacity (DL) of the lung can be divided into two components: the diffusing capacity of the alveolar membrane (Dm) and the pulmonary capillary volume (Vc).
Astrid Thomas, B. Hanel, J. Marott, F. Buchvald, J. Mortensen, K. Nielsen   +5 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source