Results 51 to 60 of about 267,585 (286)

Distortion in Diffusion Weighted Imaging

Japanese Journal of Radiological Technology, 2009
The definitional equation of the distortion of echo planar imaging(EPI)was examined. We compared measured values with calculated values by using the definitional equation of the chemical shift of the EPI method that first composed the diffusion-weighted image, and examined the possibility of applying it to the distortion.
Mitsuyuki, Takahashi, Akio, Ogura, Masanori, Ozaki, Isao, Muro, Tsukasa, Doi, Tosiaki, Miyati, Hajime, Tanji, Junji, Takahashi, Osamu, Takizawa   +8 more
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A Simplified Crossing Fiber Model in Diffusion Weighted Imaging [PDF]

, 2019
Diffusion MRI (dMRI) is a vital source of imaging data for identifying anatomical connections in the living human brain that form the substrate for information transfer between brain regions.
Carr, Sarah J. Ann, Ghosh, Kaushik, Sahoo, Satya S., Sakaie, Ken, Tatsuoka, Curtis, Yang, Sheng   +5 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Diffusion-weighted imaging and diffusion-weighted whole-body imaging with background body signal suppression for characterizing esophageal cancer: a case report

International Medical Case Reports Journal, 2013
Minoru Tomizawa,1 Fuminobu Shinozaki,2 Aika Ozaki,2 Akira Baba,2 Yoshiya Fukamizu,2 Futoshi Matsunaga,2 Takao Sugiyama,3 Shigenori Yamamoto,4 Makoto Sueishi,3 Takanobu Yoshida51Department of Gastroenterology, 2Department of Radiology, 3Department of ...
Tomizawa M, Shinozaki F, Ozaki A, Baba A, Fukamizu Y, Matsunaga F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T   +9 more
doaj  

Diagnostic Comparison of MRI Sequences for Assessing Myometrial Invasion in Endometrial Cancer: A 1.5T MRI Study

Hitit Medical Journal
Objective: To compare the diagnostic accuracy of T2-weighted, dynamic contrast-enhanced imaging, and diffusion-weighted imaging in assessing myometrial invasion depth in endometrial cancer and to determine if any sequence performs better.
Abdusselim Adil Peker, Ahmet Akçay
doaj   +1 more source

Diffusion weighted imaging and diffusion tensor imaging in the evaluation of transplanted kidneys

European Journal of Radiology Open, 2015
Objective: The aim of this study is to investigate the relation between renal indexes and functional MRI in a population of kidney transplant recipients who underwent MR with diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) of the ...
Stefano Palmucci, Giuseppina Cappello, Giancarlo Attinà, Pietro Valerio Foti, Rita Olivia Anna Siverino, Federica Roccasalva, Marina Piccoli, Nunziata Sinagra, Pietro Milone, Massimiliano Veroux, Giovanni Carlo Ettorre   +10 more
doaj   +1 more source

Technical advancements and protocol optimization of diffusion-weighted imaging (DWI) in liver [PDF]

, 2016
An area of rapid advancement in abdominal MRI is diffusion-weighted imaging (DWI). By measuring diffusion properties of water molecules, DWI is capable of non-invasively probing tissue properties and physiology at cellular and macromolecular level.
Chen, Ziqian, Lin, Chen, Lin, Yuning, Ni, Ping, Sandrasegaran, Kumar, Zhong, Qun   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Scedosporium apiospermum endophthalmitis: diffusion-weighted imaging in detecting subchoroidal abscess

Clinical Ophthalmology, 2012
Sandeep Bhuta, Charlie Chia-Tsong Hsu, Gigi Nga Chi KwanGriffith University, School of Medicine, Department of Medical Imaging, Gold Coast Hospital, Southport, Gold Coast, QLD, AustraliaPurpose: To describe the imaging appearance of Scedosporium ...
Kwan GN, Hsu CC, Bhuta S
doaj