Results 61 to 70 of about 3,370,652 (304)
BMC Ophthalmology, 2023 Background Thyroid eye disease is an extrathyroidal manifestation of Graves’ disease and is associated with dry eye disease. This is the first systematic review and meta-analysis to evaluate the role of magnetic resonance imaging lacrimal gland ...
Nicole Tsz Yan Wong +8 more
doaj +1 more source
Correcting for Motion between Acquisitions in Diffusion MR Imaging [PDF]
, 2009 The diffusion tensor (DT) and other diffusion models assume that each voxel corresponds to the same anatomical location in all the measurements. Movements and distortions violate this assumption and typically the images are realigned before model ...
Bai, Y
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
HeliyonBackground: To assess the feasibility of multiparametric magnetic resonance imaging in predicting tumor recurrence in nonenhancing peritumoral regions in patients with glioblastoma at baseline.
Zhen Xing +5 more
doaj +1 more source
Precise Characterization of the Penumbra Revealed by MRI: A Modified Photothrombotic Stroke Model Study. [PDF]
PLoS ONE, 2016 AIMS:To precisely characterize the penumbra by MRI based on a modified photothrombotic stroke mouse model. METHODS:The proximal middle cerebral artery was occluded by a convenient laser system in conjunction with an intravenous injection of Rose Bengal ...
Cheng Qian +8 more
doaj +1 more source
Probabilistic Anatomical Connectivity Derived from the Microscopic Persistent Angular Structure of Cerebral Tissue [PDF]
, 2005 Recently developed methods to extract the persistent angular structure (PAS) of axonal fibre bundles from diffusion-weighted magnetic resonance imaging (MRI) data are applied to drive probabilistic fibre tracking, designed to provide estimates of ...
Parker, Geoffrey J M +3 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Diffusion-weighted imaging in gynaecological malignancies
The Royal College of Radiologists OpenDiffusion-weighted imaging (DWI) is an important tool in the assessment of gynaecological malignancies, enhancing the field of tumor biology beyond where conventional imaging techniques have taken us.
Pranjal +5 more
doaj +1 more source